Platelets have important functions in hemostasis. Best investigated is the aggregation of
platelets for primary hemostasis and their role as the surface for coagulation leading to fibrin …

Trauma induces a change in nearly every observable aspect of hemostasis, generally
tipping the balance toward trauma-induced coagulopathy (TIC) and bleeding in the critical …

Background: Adrenaline is believed to play a role in thrombosis and hemostasis. The
complex effect of its clinically relevant concentrations on thrombus formation, coagulation …

Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying
due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD …

Chronic kidney disease (CKD) patients are at high risk for thrombotic events. Indoxyl sulfate
(IS) is one of the most potent uremic toxins that accumulates during CKD. Even though IS is …

An increase in aldosterone levels positively correlates with an increased risk of acute
cardiovascular thrombotic events. The aim of the study was to determine the mechanism of …

Hypochlorite (HOCl), a strong oxidant and antimicrobial agent, has been proposed to be
associated with hemostatic abnormalities during inflammatory response. However, its …

The aim of this study was to assess whether steroid‐naïve asthma modulates hemostasis.
We evaluated the clot retraction rate (CRR), fibrinolysis rate (FR), clot density (CD)(by …

Adrenaline has recently been found to trigger phosphatidylserine (PS) exposure on blood
platelets, resulting in amplification of the coagulation process, but the mechanism is only …

Background: Recent studies indicate that aquaporin (AQP) water channels have a
regulatory function in human platelet secretion and in procoagulant response of murine …