Mechanisms of protein trafficking and quality control in the kidney and beyond

JL Shaw, JL Pablo, A Greka - Annual Review of Physiology, 2023 - annualreviews.org
Numerous trafficking and quality control pathways evolved to handle the diversity of proteins
made by eukaryotic cells. However, at every step along the biosynthetic pathway, there is …

Tracing genetic diversity captures the molecular basis of misfolding disease

P Zhao, C Wang, S Sun, X Wang, WE Balch - Nature Communications, 2024 - nature.com
Genetic variation in human populations can result in the misfolding and aggregation of
proteins, giving rise to systemic and neurodegenerative diseases that require management …

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

S Lee, D Jee, S Srivastava, A Yang, A Ramidi, R Shang… - Cell reports, 2023 - cell.com
Canonical microRNA (miRNA) hairpins are processed by the RNase III enzymes Drosha
and Dicer into∼ 22 nt RNAs loaded into an Argonaute (Ago) effector. In addition, splicing …

Dynamic alterations in physiological and biochemical indicators of Cirrhinus mrigala hatchlings: A sublethal exposure of triclosan

OI Dar, A Vinothkanna, B Aslam, A Furkh… - Science of The Total …, 2024 - Elsevier
Triclosan (TCS), a biocide used in various day-to-day products, has been associated with
several toxic effects in aquatic organisms. In the present study, biochemical and …

Single-domain magnetic particles with motion behavior under electromagnetic AC and DC fields are a fatal cargo in Metropolitan Mexico City pediatric and young …

L Calderón-Garcidueñas, FR Cejudo-Ruiz… - Frontiers in Human …, 2024 - frontiersin.org
Metropolitan Mexico City (MMC) children and young adults exhibit overlapping Alzheimer
and Parkinsons' diseases (AD, PD) and TAR DNA-binding protein 43 pathology with …

Single-cell expression predicts neuron-specific protein homeostasis networks

S Pechmann - Open Biology, 2024 - royalsocietypublishing.org
The protein homeostasis network keeps proteins in their correct shapes and avoids
unwanted aggregation. In turn, the accumulation of aberrantly misfolded proteins has been …

2 Proteases in Cancer

S Chirumbolo, G Bjorklund… - … of Proteases in …, 2024 - api.taylorfrancis.com
Unravelling the role of different sets of proteases in cancer is challenging, because the first
concern should be highlighting the role of cancer in biological existence (Koblinski et al …

[PDF][PDF] Professional Appointments

MR Atal - Perspectives, 2021 - maha-rafi-atal.com
When Companies Rule, monograph submitted to Oxford University Press Book manuscript
considering corporate social responsibility as a governance regime and situating …