[HTML][HTML] Tissue invasion and metastasis: Molecular, biological and clinical perspectives
WG Jiang, AJ Sanders, M Katoh, H Ungefroren… - Seminars in cancer …, 2015 - Elsevier
Cancer is a key health issue across the world, causing substantial patient morbidity and
mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to …
mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to …
TGF‐β control of cell proliferation
SS Huang, JS Huang - Journal of cellular biochemistry, 2005 - Wiley Online Library
This article focuses on recent findings that the type V TGF‐β receptor (TβR‐V), which co‐
expresses with other TGF‐β receptors (TβR‐I, TβR‐II, and TβR‐III) in all normal cell types …
expresses with other TGF‐β receptors (TβR‐I, TβR‐II, and TβR‐III) in all normal cell types …
Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts
S Dooley, B Delvoux, B Lahme… - Hepatology, 2000 - journals.lww.com
Activation of hepatic stellate cells (HSCs) is the key step in liver fibrogenesis. Increased
transforming growth factor β (TGF-β) expression and extracellular matrix production in …
transforming growth factor β (TGF-β) expression and extracellular matrix production in …
Transforming growth factor-β signal transduction in epithelial cells
J Yue, KM Mulder - Pharmacology & therapeutics, 2001 - Elsevier
Transforming growth factor (TGF)-β is a natural and potent growth inhibitor of a variety of cell
types, including epithelial, endothelial, and hematopoietic cells. The ability of TGF-β to …
types, including epithelial, endothelial, and hematopoietic cells. The ability of TGF-β to …
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
S Dennler, S Huet, JM Gauthier - Oncogene, 1999 - nature.com
Smad proteins are essential components of the signalling cascade initiated by members of
the Transforming Growth Factor-β family. TGFβ binding to heteromeric complexes of …
the Transforming Growth Factor-β family. TGFβ binding to heteromeric complexes of …
The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development
T Brummel, S Abdollah, TE Haerry… - Genes & …, 1999 - genesdev.cshlp.org
The TGF-β superfamily of growth and differentiation factors, including TGF-β, Activins and
bone morphogenetic proteins (BMPs) play critical roles in regulating the development of …
bone morphogenetic proteins (BMPs) play critical roles in regulating the development of …
[HTML][HTML] Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine
R Jesnowski, D Fürst, J Ringel, Y Chen… - Laboratory …, 2005 - Elsevier
Tissue fibrosis is one of the characteristics of chronic pancreatitis and pancreatic
adenocarcinoma. Activated pancreatic stellate cells (PSC) play a central role in this process …
adenocarcinoma. Activated pancreatic stellate cells (PSC) play a central role in this process …
Cellular growth inhibition by IGFBP‐3 and TGF‐β1 requires LRP‐1
SS Huang, TY Ling, WF Tseng, YH Huang… - The FASEB …, 2003 - Wiley Online Library
The type V TGF‐β receptor (TβR‐V)/IGFBP‐3 receptor mediates the IGF‐independent
growth inhibition induced by IGFBP‐3. It also mediates the growth inhibitory response to …
growth inhibition induced by IGFBP‐3. It also mediates the growth inhibitory response to …
Administration of bone marrow stromal cells ameliorates experimental autoimmune myasthenia gravis by altering the balance of Th1/Th2/Th17/Treg cell subsets …
Q Kong, B Sun, S Bai, D Zhai, G Wang, Y Liu… - Journal of …, 2009 - Elsevier
Bone marrow stromal cells (BMSCs) are strong candidates for cell therapy against human
autoimmune diseases. Intravenous administration of syngenic BMSCs to EAMG-model rats …
autoimmune diseases. Intravenous administration of syngenic BMSCs to EAMG-model rats …
Requirement for TGFβ receptor signaling during terminal lens fiber differentiation
RU de Iongh, FJ Lovicu, PA Overbeek, MD Schneider… - 2001 - journals.biologists.com
Several families of growth factors have been identified as regulators of cell fate in the
developing lens. Members of the fibroblast growth factor family are potent inducers of lens …
developing lens. Members of the fibroblast growth factor family are potent inducers of lens …