[HTML][HTML] Design of two phase III, randomized, multicenter studies comparing gepotidacin with nitrofurantoin for the treatment of uncomplicated urinary tract infection in …

C Perry, M Hossain, M Powell, A Raychaudhuri… - Infectious Diseases and …, 2022 - Springer
Background Uncomplicated urinary tract infections (uUTIs) are among the most common
community-acquired infections for women worldwide. Treatment options are increasingly …

Therapies in preclinical and in early clinical development for the treatment of urinary tract infections: from pathogens to therapies

V Fuochi, S Furnari, L Trovato, M Calvo… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Urinary tract infections (UTIs) are a prevalent health challenge
characterized by the invasion and multiplication of microorganisms in the urinary system …

[HTML][HTML] Cystitis

R Li, SW Leslie - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Cystitis - StatPearls - NCBI Bookshelf US flag An official website of the United States government
Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Pharmacokinetic, safety, and tolerability evaluations of gepotidacin (GSK2140944) in healthy Japanese participants

A Barth, M Hossain, CR Perry, AS Gross… - Clinical …, 2023 - Wiley Online Library
Gepotidacin is a novel, bactericidal, first‐in‐class triazaacenaphthylene antibiotic in late‐
phase development for uncomplicated urinary tract infection and uncomplicated urogenital …

Clinical assessment of gepotidacin (GSK2140944) as a victim and perpetrator of drug–drug interactions via CYP3A metabolism and transporters

A Barth, CR Perry, S Shabbir… - Clinical and …, 2023 - Wiley Online Library
Gepotidacin is a novel triazaacenaphthylene antibiotic in phase III development. Based on
nonclinical in vitro characterization of gepotidacin metabolism, two phase I studies were …

[HTML][HTML] Continuing Education Activity

AY Li, S Dream - europepmc.org
Cystitis Raymund Li; Stephen W. Leslie. Author Information Last Update: May 30, 2023.
Continuing Education Activity Cystitis refers to infection of the lower urinary tract, or more …