Cell-free gene expression: methods and applications
Cell-free gene expression (CFE) systems empower synthetic biologists to build biological
molecules and processes outside of living intact cells. The foundational principle is that …
molecules and processes outside of living intact cells. The foundational principle is that …
Achieving broad availability of SARS-CoV-2 detections via smartphone-based analysis
With the development of COVID-19, widely available tests are in great demand. Naked-eye
SARS-CoV-2 test kits have recently been developed as home tests, but their sensitivity and …
SARS-CoV-2 test kits have recently been developed as home tests, but their sensitivity and …
A sensitive and specific fluorescent RT-LAMP assay for SARS-CoV-2 detection in clinical samples
KH Ooi, MM Liu, JR Moo, P Nimsamer… - ACS Synthetic …, 2022 - ACS Publications
The raging COVID-19 pandemic has created an unprecedented demand for frequent and
widespread testing to limit viral transmission. Reverse transcription loop-mediated …
widespread testing to limit viral transmission. Reverse transcription loop-mediated …
Making the next generation of therapeutics: mRNA meets synthetic biology
The development of mRNA-based therapeutics centers around the natural functioning of
mRNA molecules to provide the genetic information required for protein translation. To …
mRNA molecules to provide the genetic information required for protein translation. To …
Double loop-stem hairpins mediated hybridization chain reaction: A multifunctional DNA molecular tool to produce the intact aptamer for label-free biosensing
X Peng, J Yang, W Liang, Y Sun, X Mei, G Zhang… - Sensors and Actuators B …, 2022 - Elsevier
A DNA molecular tool based on the double loop-stem (DL) hairpins mediated hybridization
chain reaction (D-HCR) system was proposed to produce the intact G-quadruplex (InG4) …
chain reaction (D-HCR) system was proposed to produce the intact G-quadruplex (InG4) …
Synthetic biology enables field-deployable biosensors for water contaminants
Wastewater surveillance is a powerful tool to understand community profiling in terms of
health monitoring. Tracking biomarkers such as inorganic and organic pollutants, drugs, and …
health monitoring. Tracking biomarkers such as inorganic and organic pollutants, drugs, and …
Combating infectious diseases with synthetic biology
Over the past decades, there have been numerous outbreaks, including parasitic, fungal,
bacterial, and viral infections, worldwide. The rate at which infectious diseases are emerging …
bacterial, and viral infections, worldwide. The rate at which infectious diseases are emerging …
[HTML][HTML] Gene circuit-based sensors
X Guo, M Li, X Zuo - Fundamental Research, 2024 - Elsevier
As an important branch of biosensors, gene circuit-based biosensors constructed based on
synthetic biology concepts can sense specific substances to be measured and converted …
synthetic biology concepts can sense specific substances to be measured and converted …
Rapid enzymatic assays for fecal contamination in aquatic environment: challenges, advances and prospects
Routine monitoring of sanitation and hygiene to identify fecal contamination in aquatic
environments is an effective means to prevent threatening disease transmission. Compared …
environments is an effective means to prevent threatening disease transmission. Compared …
RNA-Based Sensor Systems for Affordable Diagnostics in the Age of Pandemics
In the era of the COVID-19 pandemic, the significance of point-of-care (POC) diagnostic
tools has become increasingly vital, driven by the need for quick and precise virus …
tools has become increasingly vital, driven by the need for quick and precise virus …