Hyaluronic acid and its derivatives in drug delivery and imaging: Recent advances and challenges
Hyaluronic acid (HA) is a biodegradable, biocompatible, nontoxic, and non-immunogenic
glycosaminoglycan used for various biomedical applications. The interaction of HA with the …
glycosaminoglycan used for various biomedical applications. The interaction of HA with the …
Carbohydrate-based amphiphilic nano delivery systems for cancer therapy
K Liu, X Jiang, P Hunziker - Nanoscale, 2016 - pubs.rsc.org
Nanoparticles (NPs) are novel drug delivery systems that have been attracting more and
more attention in recent years, and have been used for the treatment of cancer, infection …
more attention in recent years, and have been used for the treatment of cancer, infection …
Recent advances in pH-sensitive polymeric nanoparticles for smart drug delivery in cancer therapy
Background: Rapid developments in the field of nanoparticles during the last decades have
led to its increased application in drug delivery approaches. The advantages of nano-based …
led to its increased application in drug delivery approaches. The advantages of nano-based …
Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer
Multi-drug delivery focuses on different signaling pathways in cancer cells that have
synergistic anti-proliferative effects. In this study, we developed multi-prodrug nanocarriers …
synergistic anti-proliferative effects. In this study, we developed multi-prodrug nanocarriers …
Synthesis of hyaluronic acid-based polymersomes for doxorubicin delivery to metastatic breast cancer
In the current research, the synthesis of polysaccharide-based polymersomes for targeted
delivery of doxorubicin is reported. To this aim, doxorubicin was encapsulated in aqueous …
delivery of doxorubicin is reported. To this aim, doxorubicin was encapsulated in aqueous …
Amphiphilic polysaccharides as building blocks for self-assembled nanosystems: molecular design and application in cancer and inflammatory diseases
Polysaccharides (PSs) have been extensively studied in healthcare applications; here, we
focus our attention on their use as components of nanomaterials in the management of …
focus our attention on their use as components of nanomaterials in the management of …
Nanovesicle-mediated systemic delivery of microRNA-34a for CD44 overexpressing gastric cancer stem cell therapy
The cancer stem cell (CSC) hypothesis postulates that cancer cells overexpressing CD44
are marked as CSCs that cause tumorigenesis and recurrence. This hypothesis suggests …
are marked as CSCs that cause tumorigenesis and recurrence. This hypothesis suggests …
Magnetic nanochain-based smart drug delivery system with remote tunable drug release by a magnetic field
Considerable attention is given to drug delivery technology that efficiently delivers
appropriate levels of drug molecules to diseased sites with significant therapeutic efficacy …
appropriate levels of drug molecules to diseased sites with significant therapeutic efficacy …
Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy
Smart drug delivery systems that are triggered by environmental conditions have been
developed to enhance cancer therapeutic efficacy while limiting unwanted effects. Because …
developed to enhance cancer therapeutic efficacy while limiting unwanted effects. Because …
Hyaluronic Acid-Decorated Laponite® Nanocomposites for Targeted Anticancer Drug Delivery
T Jiang, G Chen, X Shi, R Guo - Polymers, 2019 - mdpi.com
In this study, hyaluronic acid (HA), a natural polysaccharide that can specifically bind to
CD44 receptors, was conjugated onto laponite®(LAP) nanodisks for the encapsulation and …
CD44 receptors, was conjugated onto laponite®(LAP) nanodisks for the encapsulation and …