High Energy Musculoskeletal Traumas (HEMTs) represent a relevant problem for healthcare
systems, considering the high social costs, and both the high morbidity and mortality. The …

Background and Objectives: Wound healing is commonly associated with critical bacterial
colonization or bacterial infection, which induces prolonged inflammation, resulting in …

Background and objectives: Complex limb traumas are commonly treated with microsurgical
reconstruction and free flaps. However, complications are frequent in patients affected by a …

Background: Wound bed preparation is an important concept in clinical practice and is
related to adequate debridement. The use of proteolytic enzymes is an established method …

Background: During negative pressure wound therapy (NPWT), open wounds are draped
with a nontransparent sponge, making daily wound evaluation impossible. Sometimes, late …

Objective: The reconstruction of complex soft tissue defects with exposure of bones and
tendons represents an increasing challenge in wound care, especially in large extremity …

Hard-to-heal wounds are an important public health issue worldwide, with a significant
impact on the quality of life of patients. It is estimated that approximately 1–2% of the global …

OBJECTIVE: This study aims to evaluate the etiology of upper extremity soft tissue defects
and determine the outcome of the various methods for covering upper limb soft tissue …

Introduction Nature has provided living bodies with extraordinary active reparative
mechanisms. Besides these biological processes anatomical structures are designed to …