Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …

Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …

Rationale: Embryonic stem cells (ESCs) hold great promise for cardiac regeneration but are
susceptible to various concerns. Recently, salutary effects of stem cells have been …

The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has
recently been exploited for the treatment of diseases. For example, EVs secreted by …

Background/Aims: Bone marrow mesenchymal stem cells (MSCs) widely applied for treating
myocardial infarction face survival challenges in the inflammatory and ischemia …

Mesenchymal stem cells (MSCs), whose mechanism of action is predominantly paracrine,
are being widely tested for the treatment of a variety of human diseases. No one factor has …

The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell
survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the …

Background Exosomes play an important role in intercellular signaling and exert regulatory
function by carrying bioactive molecules. This study investigated (1) the cardioprotective …