Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …

Ultrasensitive nanomechanical instruments, eg atomic force microscopy (AFM), can be used
to perform delicate biomechanical measurements and reveal the complex mechanical …

Simple assay format-based SERS methods for sensitive target substance analysis is of great
significance for the development of on-site monitoring biosensors. Herein, taking the typical …

Tissue mechanobiology is an emerging field with the overarching goal of understanding the
interplay between biophysical and biochemical responses affecting development …

The mechanical properties of the skin determine tissue function and regulate dermal cell
behavior. Yet measuring these properties remains challenging, as evidenced by the large …

The intestine performs functions central to human health by breaking down food and
absorbing nutrients while maintaining a selective barrier against the intestinal microbiome …

3D gradient printing is a type of fabrication technique that additively builds three-
dimensional objects with gradually changing properties. Gradient digital light processing …

Re-creating features of the native extracellular matrix (ECM) with engineered biomaterials
has become a valuable tool to probe the influence of ECM properties on cellular functions …