Pharmacovigilance in low‐and middle‐income countries: a review with particular focus on Africa

R Kiguba, S Olsson, C Waitt - British journal of clinical …, 2023 - Wiley Online Library
Low‐and middle‐income countries (LMIC) face unique challenges with regard to the
establishment of robust pharmacovigilance systems capable of generating data to inform …

Frequency, severity, and factors associated with clinically significant drug-drug interactions among patients with cancer attending Mbarara Regional Referral Hospital …

B Luzze, B Atwiine, HM Lugobe, TM Yadesa - BMC cancer, 2022 - Springer
Background Cancer is a major public health problem with pharmacotherapy being the
cornerstone of its management. Cancer patients receive multiple drugs concurrently risking …

Prevalence and factors associated with adverse drug reactions among heart failure patients hospitalized at Mbarara Regional Referral Hospital, Uganda

EA Shegena, KA Nigussie, R Tamukong… - BMC Cardiovascular …, 2022 - Springer
Background Adverse drug reaction (ADR) of medications remains an obstacle to achieving
optimal disease outcomes. This study aimed to assess the prevalence and associated …

Inconsistent country-wide reporting of adverse drug reactions to antimicrobials in Sierra Leone (2017–2021): a Wake-up call to improve reporting

F Thomas, OT Abiri, JP Komeh, TA Conteh… - International Journal of …, 2022 - mdpi.com
Background: Monitoring of adverse drug reactions (ADRs) to antimicrobials is important, as
they can cause life-threatening illness, permanent disabilities, and death. We assessed …

The 2011–2020 trends of data-driven approaches in medical informatics for active pharmacovigilance

H Shin, J Cha, C Lee, H Song, H Jeong, JY Kim… - Applied Sciences, 2021 - mdpi.com
Pharmacovigilance, the scientific discipline pertaining to drug safety, has been studied
extensively and is progressing continuously. In this field, medical informatics techniques and …

An analysis of the trends, characteristics, scope, and performance of the Zimbabwean pharmacovigilance reporting scheme

JT Masuka, S Khoza - Pharmacology Research & Perspectives, 2020 - Wiley Online Library
We aimed to determine the reporting trends and characteristics of Individual Case Safety
Reports (ICSRs) from the Zimbabwean national pharmacovigilance system. ICSRs …

Profile of adverse drug reaction reports in South Africa: An analysis of VigiBase for the year 2017

MF Matlala, MS Lubbe, H Steyn - South African Medical Journal, 2023 - journals.co.za
Background The South African Health Products Regulatory Authority (SAHPRA) monitors
the safety of health products by collecting and evaluating adverse drug reaction (ADR) …

A retrospective review of serious adverse drug reaction reports in the Nigerian VigiFlow database from September 2004 to December 2016

CK Ogar, A Abiola, D Yuah, A Ibrahim… - Pharmaceutical …, 2019 - Springer
Abstract Background Adverse drug reactions (ADRs) are a source of concern in healthcare
as they negatively affect patients. Serious adverse drug reactions (SADRs) have an even …

Implementation of a peer support intervention to promote the detection, reporting and management of adverse drug reactions in people living with HIV in Uganda: a …

R Kiguba, HB Ndagije, V Nambasa, C Katureebe… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Patients have contributed< 1% of spontaneous adverse drug reaction (ADR)
reports in Uganda's pharmacovigilance database. Peer support combined with mobile …

Effectiveness of the Med Safety mobile application in improving adverse drug reaction reporting by healthcare professionals in Uganda: a protocol for a pragmatic …

R Kiguba, N Mwebaza, R Ssenyonga, HB Ndagije… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Combination antiretroviral therapy (cART) has massively reduced HIV mortality.
However, long-term cART increases the risk of adverse drug reactions (ADRs), which can …