Nervonic acid (NA) has attracted considerable attention because of its close relationship
with brain development. Sources of NA include oil crop seeds, oil-producing microalgae …

Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …

Nervonic acid has proven efficacy in brain development and the prevention of
neurodegenerative diseases. Here, an alternative and sustainable strategy for nervonic acid …

Background The risk for dementia increases exponentially from the seventh decade of life.
Identifying and understanding the biochemical changes that sensitize the ageing brain to …

Nervonic acid (NA) is a very-long-chain monounsaturated fatty acid that plays crucial roles in
brain development and has attracted widespread research interest. The markets …

The endoplasmic reticulum (ER) plays a key role in the regulation of protein folding, lipid
synthesis, calcium homeostasis, and serves as a primary site of sphingolipid biosynthesis …

Lipids are the major component of the brain with important structural and functional
properties. Lipid disruption could play a relevant role in Alzheimer's disease (AD). Some …

Lipids are essential in maintaining brain function, and lipid profiles have been reported to be
altered in aged and Alzheimer's disease (AD) brains as compared to healthy mature brains …

Abstract Bioactive sphingolipids: sphingosine, sphingosine-1-phosphate (S1P), ceramide,
and ceramide-1-phosphate (C1P) are increasingly implicated in cell survival, proliferation …

Recently, extracellular vesicles (EVs), such as exosomes, have been proposed to play an
influential role in the cell-to-cell spread of neurodegenerative diseases, including the …