Nigella sativa: phytochemistry, pharmacology and its therapeutic potential

P Tiwari, S Jena, S Satpathy… - Research Journal of …, 2019 - indianjournals.com
Nigella sativa belonging to family ranunculaceae. This plant is an extensively used as
medicinal plant in India as well as all over the world. Nigella sativa (N. sativa) is well known …

[HTML][HTML] Antimicrobial Properties and Therapeutic Potential of Bioactive Compounds in Nigella sativa: A Review

M Abbas, MA Gururani, A Ali, S Bajwa, R Hassan… - Molecules, 2024 - mdpi.com
Nigella sativa (N. sativa; Ranunculaceae), commonly referred to as black cumin, is one of
the most widely used medicinal plants worldwide, with its seeds having numerous …

Assessment of protective potential of Nigella sativa oil against carbendazim- and/or mancozeb-induced hematotoxicity, hepatotoxicity, and genotoxicity

MA Hashem, WAM Mohamed, ESM Attia - Environmental Science and …, 2018 - Springer
Nigella sativa oil (NSO) possesses antioxidant activity. However, its protective role against
the hazards of fungicides has been poorly studied. Therefore, the present work aimed at …

Role of oxidative stress, MAPKinase and apoptosis pathways in the protective effects of thymoquinone against acrylamide-induced central nervous system toxicity in …

J Tabeshpour, S Mehri, K Abnous… - Neurochemical …, 2020 - Springer
The present study evaluated biochemical endpoints characterizing acrylamide (ACR)
neurotoxicity in the cortex of rats, following the possible neuroprotective activity of …

Evaluation of the effect of thymoquinone in d‐galactose‐induced memory impairments in rats: Role of MAPK, oxidative stress, and neuroinflammation pathways and …

Z Oskouei, S Mehri, F Kalalinia… - Phytotherapy …, 2021 - Wiley Online Library
d‐galactose (d‐gal) induces aging and memory impairment via oxidative stress and
neuroinflammation pathways. This study evaluated the neuroprotective activity of …

Neuroprotective effects of Nigella sativa extract upon the hippocampus in PTU-induced hypothyroidism juvenile rats: A stereological study

F Asiaei, A Fazel, AA Rajabzadeh, M Hosseini… - Metabolic brain …, 2017 - Springer
This study aimed to examine the neuroprotective effects of Nigella sativa (N. sativa) in the
hippocampus of propylthiouracil (PTU)-induced hypothyroid rats during neonatal and …

Potential herb-drug interaction risk of thymoquinone and phenytoin

Z Wang, X Wang, Z Wang, X Lv, H Yin, W Li… - Chemico-Biological …, 2022 - Elsevier
Thymoquinone is a main bioactive compound of Nigella sativa L.(N. sativa), which has been
used for clinical studies in the treatment of seizures due to its beneficial neuroprotective …

Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment …

R Kulkarni, R Mehta, SK Goswami… - Biochemical and …, 2023 - Elsevier
Chemotherapy-induced cognitive impairment (CICI) is a novel clinical condition
characterized by memory, learning, and motor function deficits. Oxidative stress and …

Anxiolytic-like effect of pyridoxine in mice by elevated plus maze and light and dark box: Evidence for the involvement of GABAergic and NO-sGC-cGMP pathway

V Walia, C Garg, M Garg - Pharmacology Biochemistry and Behavior, 2018 - Elsevier
Present study was carried out to investigate the 'anxiolytic-like'effect of pyridoxine in mice.
Pyridoxine (90, 180 and 360 mg/kg) was administered by intraperitoneal (ip) route to the …

[HTML][HTML] Phytocompounds of Nigella sativa seeds extract and their neuroprotective potential via EGR1 receptor inhibition: A molecular docking study

K Kulsum, S Syahrul, K Hasbalah, U Balqis - Narra J, 2023 - ncbi.nlm.nih.gov
Bioactivity of Nigella sativa seed extract has the potential as a neuro-protector, offering its
promising utility in the clinical setting for brain injury management. This study aimed to …