Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
Adenovirus: The First Effective In Vivo Gene Delivery Vector
RG Crystal - Human gene therapy, 2014 - liebertpub.com
The adenovirus, an 80–100 nm, nonenveloped, icosa-hedral capsid, double-stranded DNA
virus, is a wellknown cause of respiratory tract infections (Ginsberg, 1984). Adenovirus …
virus, is a wellknown cause of respiratory tract infections (Ginsberg, 1984). Adenovirus …
The neurobiology of addiction
GR Uhl, GF Koob, J Cable - Annals of the New York Academy …, 2019 - Wiley Online Library
Substance and alcohol use disorders impose large health and economic burdens on
individuals, families, communities, and society. Neither prevention nor treatment efforts are …
individuals, families, communities, and society. Neither prevention nor treatment efforts are …
Development of vaccines to treat opioid use disorders and reduce incidence of overdose
M Pravetoni, SD Comer - Neuropharmacology, 2019 - Elsevier
Vaccines offer a promising therapeutic strategy to treat substance use disorders (SUD).
Vaccines have shown extensive preclinical proof of selectivity, safety, and efficacy against …
Vaccines have shown extensive preclinical proof of selectivity, safety, and efficacy against …
[图书][B] The myth of the moral brain: The limits of moral enhancement
H Wiseman - 2016 - books.google.com
An argument that moral functioning is immeasurably complex, mediated by biology but not
determined by it. Throughout history, humanity has been seen as being in need of …
determined by it. Throughout history, humanity has been seen as being in need of …
Environmental, genetic and epigenetic contributions to cocaine addiction
RC Pierce, B Fant, SE Swinford-Jackson… - …, 2018 - nature.com
Decades of research on cocaine has produced volumes of data that have answered many
important questions about the nature of this highly addictive drug. Sadly, none of this …
important questions about the nature of this highly addictive drug. Sadly, none of this …
Conjugate vaccine immunotherapy for substance use disorder
PT Bremer, KD Janda - Pharmacological reviews, 2017 - ASPET
Substance use disorder, especially in relation to opioids such as heroin and fentanyl, is a
significant public health issue and has intensified in recent years. As a result, substantial …
significant public health issue and has intensified in recent years. As a result, substantial …
Development of a clinically viable heroin vaccine
Heroin is a highly abused opioid and incurs a significant detriment to society worldwide. In
an effort to expand the limited pharmacotherapy options for opioid use disorders, a heroin …
an effort to expand the limited pharmacotherapy options for opioid use disorders, a heroin …
Effectiveness of secondary prevention and treatment interventions for crack-cocaine abuse: a comprehensive narrative overview of English-language studies
There are an estimated several million crack-cocaine users globally; use is highest in the
Americas. Most crack users are socio-economically marginalized (eg, homeless), and …
Americas. Most crack users are socio-economically marginalized (eg, homeless), and …
Nanoparticle delivery systems for substance use disorder
V Kasina, RJ Mownn, R Bahal, GC Sartor - Neuropsychopharmacology, 2022 - nature.com
Innovative breakthroughs in nanotechnology are having a substantial impact in healthcare,
especially for brain diseases where effective therapeutic delivery systems are desperately …
especially for brain diseases where effective therapeutic delivery systems are desperately …