The zebrafish as a model for complex tissue regeneration
M Gemberling, TJ Bailey, DR Hyde, KD Poss - Trends in genetics, 2013 - cell.com
For centuries, philosophers and scientists have been fascinated by the principles and
implications of regeneration in lower vertebrate species. Two features have made zebrafish …
implications of regeneration in lower vertebrate species. Two features have made zebrafish …
Model systems for regeneration: zebrafish
IJ Marques, E Lupi, N Mercader - Development, 2019 - journals.biologists.com
Tissue damage can resolve completely through healing and regeneration, or can produce
permanent scarring and loss of function. The response to tissue damage varies across …
permanent scarring and loss of function. The response to tissue damage varies across …
Acute inflammation initiates the regenerative response in the adult zebrafish brain
The zebrafish regenerates its brain after injury and hence is a useful model organism to
study the mechanisms enabling regenerative neurogenesis, which is poorly manifested in …
study the mechanisms enabling regenerative neurogenesis, which is poorly manifested in …
Radial glia in the zebrafish brain: Functional, structural, and physiological comparison with the mammalian glia
The neuroscience community has witnessed a tremendous expansion of glia research. Glial
cells are now on center stage with leading roles in the development, maturation, and …
cells are now on center stage with leading roles in the development, maturation, and …
Effects of inflammation on stem cells: together they strive?
Inflammation entails a complex set of defense mechanisms acting in concert to restore the
homeostatic balance in organisms after damage or pathogen invasion. This immune …
homeostatic balance in organisms after damage or pathogen invasion. This immune …
Two phenotypically and functionally distinct microglial populations in adult zebrafish
S Wu, LTM Nguyen, H Pan, S Hassan, Y Dai, J Xu… - Science …, 2020 - science.org
Microglia are the tissue-resident macrophages in the central nervous system and are
critically involved in immune defense, neural development and function, and …
critically involved in immune defense, neural development and function, and …
IL4/STAT6 signaling activates neural stem cell proliferation and neurogenesis upon Amyloid-β42 aggregation in adult zebrafish brain
Human brains are prone to neurodegeneration, given that endogenous neural
stem/progenitor cells (NSPCs) fail to support neurogenesis. To investigate the molecular …
stem/progenitor cells (NSPCs) fail to support neurogenesis. To investigate the molecular …
Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain
Motile cilia defects impair cerebrospinal fluid (CSF) flow and can cause brain and spine
disorders. The development of ciliated cells, their impact on CSF flow, and their function in …
disorders. The development of ciliated cells, their impact on CSF flow, and their function in …
Single-cell transcriptomics analyses of neural stem cell heterogeneity and contextual plasticity in a zebrafish brain model of amyloid toxicity
The neural stem cell (NSC) reservoir can be harnessed for stem cell-based regenerative
therapies. Zebrafish remarkably regenerate their brain by inducing NSC plasticity in a …
therapies. Zebrafish remarkably regenerate their brain by inducing NSC plasticity in a …
[HTML][HTML] Serotonergic modulation of zebrafish behavior: Towards a paradox
AM Herculano, C Maximino - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Due to the fish-specific genome duplication event (~ 320–350 mya), some genes which
code for serotonin proteins were duplicated in teleosts; this duplication event was preceded …
code for serotonin proteins were duplicated in teleosts; this duplication event was preceded …