Cell death pathways: molecular mechanisms and therapeutic targets for cancer
S Wang, S Guo, J Guo, Q Du, C Wu, Y Wu… - MedComm, 2024 - Wiley Online Library
Cell death regulation is essential for tissue homeostasis and its dysregulation often
underlies cancer development. Understanding the different pathways of cell death can …
underlies cancer development. Understanding the different pathways of cell death can …
NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer
M Yu, M Ni, F Xu, C Liu, L Chen, J Li, S Xia, Y Diao… - Molecular Cancer, 2024 - Springer
Background Radioresistance is the leading cause of death in advanced cervical cancer
(CC). Dysregulation of RNA modification has recently emerged as a regulatory mechanism …
(CC). Dysregulation of RNA modification has recently emerged as a regulatory mechanism …
TRIAL-based combination therapies in cancers
Q Deng, L Chen, G Zhang, L Liu, SM Luo… - International …, 2024 - Elsevier
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) shows promising
therapeutic potential in cancer treatment as it is able to trigger extrinsic apoptotic pathways …
therapeutic potential in cancer treatment as it is able to trigger extrinsic apoptotic pathways …
Selenium Nanoparticles Enhance NK Cell‐Mediated Tumoricidal Activity in Malignant Pleural Effusion via the TrxR1‐IL‐18RAP‐pSTAT3 Pathway
Malignant pleural effusion (MPE) poses a significant challenge in local treatment, primarily
attributed to its intricate tumor immune microenvironment. The immunosuppression of …
attributed to its intricate tumor immune microenvironment. The immunosuppression of …
[HTML][HTML] The Role of TRAIL Signaling in Cancer: Searching for New Therapeutic Strategies
C Luo, S He, F Shi, J Zhou, L Shang - Biology, 2024 - mdpi.com
Simple Summary In the realm of modern medicine, the battle against cancer is a relentless
pursuit that demands continuous innovation. Among the numerous elements in the complex …
pursuit that demands continuous innovation. Among the numerous elements in the complex …
Empowering radiotherapy: Harnessing nanomedicines to enhance radiation response and boost antitumor efficacy
X Zhuo, R Aishajiang, Y Liang, P Du, P Lei, D Yu… - Coordination Chemistry …, 2024 - Elsevier
Radiotherapy (RT) is a conventional form of tumor treatment that uses X-ray irradiation to
eliminate tumors. Although RT plays an important role in treating tumor patients and …
eliminate tumors. Although RT plays an important role in treating tumor patients and …
Peptide-based PET/CT imaging visualizes PD-L1-driven radioresistance in glioblastoma
Y Wang, Z Liu, Y Li, K Wang, C Yuan, J Shi, J Ren… - Drug Resistance …, 2025 - Elsevier
Radioresistance remains a great challenge for radiotherapy in the treatment of glioblastoma
(GBM). PD-L1 expression is a key contributor to radioresistance and immune escape in …
(GBM). PD-L1 expression is a key contributor to radioresistance and immune escape in …
[HTML][HTML] Metformin induces apoptosis in TRAIL-resistant colorectal cancer cells
HM Lee, Y Jun, SY Choi, SJ Lee, OS Kwon - Biochimica et Biophysica …, 2025 - Elsevier
Resistance to chemotherapy drugs, which commonly occurs during the treatment of
colorectal cancer (CRC), can lead to tumor recurrence and metastasis, so combinational …
colorectal cancer (CRC), can lead to tumor recurrence and metastasis, so combinational …
Research progress on selenium system in cancer therapy: Focus on interface modifications and improvement of interactions
H He, D Huang, P Xie, J Dong, S Huo, S Li, L Ma… - Surfaces and …, 2024 - Elsevier
Cancer poses a grave threat to human life and health, with drug therapy being a primary
method widely employed in clinical oncology. However, the toxic side effects of these drugs …
method widely employed in clinical oncology. However, the toxic side effects of these drugs …
Mapping evolution and trends of cell membrane-coated nanoparticles: A bibliometric analysis and scoping review
C Li, J Hu, J He, C He - Nanotechnology Reviews, 2024 - degruyter.com
The limitations of traditional drug therapy have driven the creation and development of novel
cell membrane-coated nanoparticle (CMNP) platforms. Since the introduction of the CMNP …
cell membrane-coated nanoparticle (CMNP) platforms. Since the introduction of the CMNP …