Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex
Brain structure scaffolds intrinsic function, supporting cognition and ultimately behavioral
flexibility. However, it remains unclear how a static, genetically controlled architecture …
flexibility. However, it remains unclear how a static, genetically controlled architecture …
Early and late development of hub connectivity in the human brain
Human brain networks undergo pronounced changes during development. The emergence
of highly connected hub regions that can support integrated brain function is central to this …
of highly connected hub regions that can support integrated brain function is central to this …
Sensitive period diversity: Insights from evolutionary models
Recent models of the evolution of sensitive periods in response to informative stimuli (ie,
cues) provide insights into reasons why empiricists within and across disciplines might …
cues) provide insights into reasons why empiricists within and across disciplines might …
A phylogenetically-conserved axis of thalamocortical connectivity in the human brain
The thalamus enables key sensory, motor, emotive, and cognitive processes via
connections to the cortex. These projection patterns are traditionally considered to originate …
connections to the cortex. These projection patterns are traditionally considered to originate …
Benchmarking brain organoid recapitulation of fetal corticogenesis
Brain organoids are becoming increasingly relevant to dissect the molecular mechanisms
underlying psychiatric and neurological conditions. The in vitro recapitulation of key features …
underlying psychiatric and neurological conditions. The in vitro recapitulation of key features …
Non-muscle myosins control radial glial basal endfeet to mediate interneuron organization
BR D'Arcy, AL Lennox, C Manso Musso, A Bracher… - Plos …, 2023 - journals.plos.org
Radial glial cells (RGCs) are essential for the generation and organization of neurons in the
cerebral cortex. RGCs have an elongated bipolar morphology with basal and apical endfeet …
cerebral cortex. RGCs have an elongated bipolar morphology with basal and apical endfeet …
Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development
Summary mRNA localization and local translation enable exquisite spatial and temporal
control of gene expression, particularly in polarized, elongated cells. These features are …
control of gene expression, particularly in polarized, elongated cells. These features are …
Plasticity of thalamocortical axons is regulated by serotonin levels modulated by preterm birth
A Sinclair-Wilson, A Lawrence… - Proceedings of the …, 2023 - National Acad Sciences
Sensory inputs are conveyed to distinct primary areas of the neocortex through specific
thalamocortical axons (TCA). While TCA have the ability to reorient postnatally to rescue …
thalamocortical axons (TCA). While TCA have the ability to reorient postnatally to rescue …
Species-shared and-unique gyral peaks on human and macaque brains
Cortical folding is an important feature of primate brains that plays a crucial role in various
cognitive and behavioral processes. Extensive research has revealed both similarities and …
cognitive and behavioral processes. Extensive research has revealed both similarities and …
Species-shared and-unique gyral peaks on human and macaque brains
Cortical folding is an important feature of primate brains that plays a crucial role in various
cognitive and behavioral processes. Extensive research has revealed both similarities and …
cognitive and behavioral processes. Extensive research has revealed both similarities and …