Poxviruses (PXVs) are mostly known for the variola virus, being the cause of smallpox;
however, re-emerging PXVs have also shown a great capacity to develop outbreaks of pox …

Dendritic cells (DC) play critical roles in linking innate and adaptive immunity. DC are
heterogenous and there are subsets with various distinct functions. One DC subset …

Plasmacytoid dendritic cells (pDCs) are the main source of type I interferon (IFN-I) during
viral infections. Their other functions are debated, due to a lack of tools to identify and target …

Platelet homeostasis is essential for vascular integrity and immune defence,. Although the
process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has …

DCs do not just excel in antigen presentation. They orchestrate information transfer from
innate to adaptive immunity by sensing and integrating a variety of danger signals, and …

Background Eating behaviors contribute to disproportionate energy intake and are linked to
the development of obesity. Animal studies support the role of inflammatory cytokines and …

Besides their well-known role in initiating adaptive immune responses, several groups have
studied the role of dendritic cells (DCs) in the context of chronic metabolic inflammation …

Abstract Background Venezuelan Equine Encephalitis virus (VEEV) may enter the central
nervous system (CNS) within olfactory sensory neurons (OSN) that originate in the nasal …

Plasmacytoid dendritic cells (pDCs) are major producers of type I/III interferons. As these
cytokines are crucial for antiviral defense, it is assumed to be also the case for pDCs …

Natural killer (NK) lymphocytes belong to the innate lymphoid cells, which have a cytotoxic
effect on target cells and are capable of producing a large number of regulatory factors …