Objectives To present historical and contemporary hypotheses on the pathogenesis of
benign prostatic hyperplasia (BPH), and the potential implications for current medical …

The human prostate is a walnut-sized organ at the base of the urinary bladder. It is the seat
of three major causes of morbidity:(1) benign prostatic hyperplasia (BPH),(2) prostate …

Autoimmune (AI) diseases can affect many organs; however, the prostate has not been
considered to be a primary target of these systemic inflammatory processes. Here, we utilize …

Benign prostatic hyperplasia (BPH) is a benign enlargement of the prostate in which
incidence increases linearly with age, beginning at about 50 years old. BPH is a significant …

Background To explore the potential mechanisms of SARS-CoV-2 in targeting the prostate
gland, leading to exacerbation of benign prostatic hyperplasia (BPH) symptoms and greater …

Purpose: The expression of AR-V7 (androgen receptor splice variant) 7 in circulating tumor
cells has been associated with resistance to abiraterone and enzalutamide in patients with …

Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in
the initiation, development and progression of prostate cancer (PCa). Numerous papers in …

Qianliexin capsule (QLX) is a standardized traditional Chinese herbal preparation that has
long been used to treat chronic non‐bacterial prostatitis (CNP) and benign prostatic …

Benign prostatic hyperplasia (BPH) is a common male disorder. Febuxostat is a non-purine,
selective inhibitor of xanthine oxidase (XO), which has a strong antioxidant capacity and …

The oxidized low-density lipoprotein receptor 1 (LOX-1) is one of the most important
receptors for modified LDLs, such as oxidated (oxLDL) and acetylated (acLDL) low-density …