Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis
(PCM), an important endemic mycosis in Latin America. During its evolution, these fungi …

The thermally dimorphic fungi are a unique group of fungi within the Ascomycota phylum
that respond to shifts in temperature by converting between hyphae (22–25° C) and yeast …

Pathogenic fungi have developed many strategies to evade the host immune system.
Multiple escape mechanisms appear to function together to inhibit attack by the various …

Background The genus Paracoccidioides comprises human thermal dimorphic fungi, which
cause paracoccidioidomycosis (PCM), an important mycosis in Latin America. Adaptation to …

Iron is essential for the proliferation of fungal pathogens during infection. The availability of
iron is limited due to its association with host proteins. Fungal pathogens have evolved …

A common theme across multiple fungal pathogens is their ability to impair the
establishment of a protective immune response. Although early inflammation is beneficial in …

MicroRNAs (miRNAs) are small RNAs (length, 19-24 nucleotides) that regulate gene
expression by either mRNA degradation or translational inhibition of proteins. Circulating …

The dimorphic fungi Paracoccidioides spp. are the etiological agents of
paracoccidioidomycosis (PCM), a mycosis of high incidence in Brazil. The toxicity of drug …

Few virulence factors have been identified for Paracoccidioides brasiliensis, the agent of
paracoccidioidomycosis. In this study, we quantitatively evaluated the protein composition of …

Paracoccidioides spp. is the etiologic agent of Paracoccidioidomycosis (PCM), a systemic
disease with wide distribution in Latin America. Macrophages are very important cells during …