Molecular mechanisms of oxidative stress in asthma

C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management

Q Jiang, S Im, JG Wagner, ML Hernandez… - Free Radical Biology and …, 2022 - Elsevier
Abstract γ-Tocopherol (γT) is a major form of vitamin E in the US diet and the second most
abundant vitamin E in the blood and tissues, while α-tocopherol (αT) is the predominant …

Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites

Q Jiang - Free Radical Biology and Medicine, 2022 - Elsevier
Natural forms of vitamin E comprise four tocopherols and four tocotrienols. During the last
twenty years, there have been breakthroughs in our understanding of vitamin E metabolism …

Different Roles of Tocopherols and Tocotrienols in Chemoprevention and Treatment of Prostate Cancer

Q Jiang - Advances in Nutrition, 2024 - pmc.ncbi.nlm.nih.gov
The vitamin E family contains α-tocopherol (αT), βT, γT, and δT and α-tocotrienol (TE), βTE,
γTE, and δTE. Research has revealed distinct roles of these vitamin E forms in prostate …

Profile of fatty acids, tocopherols, phytosterols and polyphenols in mediterranean oils (argan oils, olive oils, milk thistle seed oils and nigella seed oil) and evaluation of …

A Zarrouk, L Martine, S Grégoire, T Nury… - Current …, 2019 - ingentaconnect.com
Background: The effects of vegetable oils on human health depend on their components.
Therefore, their profiles of lipid nutrients and polyphenols were determined. Objective: To …

Integrative analysis of the intestinal metabolome of childhood asthma

KA Lee-Sarwar, RS Kelly, J Lasky-Su, RS Zeiger… - Journal of Allergy and …, 2019 - Elsevier
Background The intestinal metabolome reflects the biological consequences of diverse
exposures and might provide insight into asthma pathophysiology. Objective We sought to …

[HTML][HTML] The effects of twenty-four nutrients and phytonutrients on immune system function and inflammation: A narrative review

J Poles, E Karhu, M McGill, HR McDaniel… - Journal of clinical and …, 2021 - ncbi.nlm.nih.gov
Methods: A comprehensive literature search of PubMed was performed to find clinical trials
in humans that assessed the effect of nutrients and phytonutrients on immune function and …

Oxidative stress promotes corticosteroid insensitivity in asthma and COPD

BW Lewis, ML Ford, LK Rogers, RD Britt Jr - Antioxidants, 2021 - mdpi.com
Corticosteroid insensitivity is a key characteristic of patients with severe asthma and COPD.
These individuals experience greater pulmonary oxidative stress and inflammation, which …

The contribution of oxidative stress and inflamm-aging in human and equine asthma

M Bullone, JP Lavoie - International journal of molecular sciences, 2017 - mdpi.com
Aging is associated with a dysregulation of the immune system, leading to a general pro-
inflammatory state of the organism, a process that has been named inflamm-aging …

Natural forms of vitamin E and metabolites—regulation of cancer cell death and underlying mechanisms

Q Jiang - IUBMB life, 2019 - Wiley Online Library
The disappointing results from large clinical studies of α‐tocopherol (αT), the major form of
vitamin E in tissues, for prevention of chronic diseases including cancer have cast doubt on …