Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
D Vuckovic - Analytical and bioanalytical chemistry, 2012 - Springer
The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …
because it affects both the observed metabolite content and biological interpretation of the …
Gas chromatography/mass spectrometry in metabolic profiling of biological fluids
One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …
between biological systems of different physiological or pathological states. Gas …
Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry
ECY Chan, KK Pasikanti, JK Nicholson - Nature protocols, 2011 - nature.com
The role of urinary metabolic profiling in systems biology research is expanding. This is
because of the use of this technology for clinical diagnostic and mechanistic studies and for …
because of the use of this technology for clinical diagnostic and mechanistic studies and for …
Estrogenic endocrine-disrupting chemicals: molecular mechanisms of actions on putative human diseases
Endocrine-disrupting chemicals (EDC), including phthalates, bisphenol A (BPA),
phytoestrogens such as genistein and daidzein, dichlorodiphenyltrichloroethane (DDT), and …
phytoestrogens such as genistein and daidzein, dichlorodiphenyltrichloroethane (DDT), and …
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry
(GC× GC–TOFMS) coupled with pattern recognition methods was applied to analyze plasma …
(GC× GC–TOFMS) coupled with pattern recognition methods was applied to analyze plasma …
Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers
BACKGROUND: The metabolomic approaches for mining biomarkers of women's cancers
based on gas chromatography-mass spectrometry and liquid chromatography-mass …
based on gas chromatography-mass spectrometry and liquid chromatography-mass …
Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry
With unmatched mass resolution, mass accuracy, and exceptional detection sensitivity,
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FTICR-MS) has the …
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FTICR-MS) has the …
Metabolomics in pesticide research and development: review and future perspectives
KA Aliferis, M Chrysayi-Tokousbalides - Metabolomics, 2011 - Springer
The emerge of metabolomics within functional genomics has provided a new dimension in
the study of biological systems. In regards to the study of agroecosystems, metabolomics …
the study of biological systems. In regards to the study of agroecosystems, metabolomics …
Virtual quantification of metabolites by capillary electrophoresis-electrospray ionization-mass spectrometry: predicting ionization efficiency without chemical standards
KR Chalcraft, R Lee, C Mills… - Analytical …, 2009 - ACS Publications
A major obstacle in metabolomics remains the identification and quantification of a large
fraction of unknown metabolites in complex biological samples when purified standards are …
fraction of unknown metabolites in complex biological samples when purified standards are …
Mass spectrometry in systems biology: an overview
X Feng, X Liu, Q Luo, BF Liu - Mass spectrometry reviews, 2008 - Wiley Online Library
As an emerging field, systems biology is currently the talk of the town, which challenges our
philosophy in comprehending biology. Instead of the reduction approach advocated in …
philosophy in comprehending biology. Instead of the reduction approach advocated in …