Paired-box (PAX) genes encode a family of highly conserved transcription factors found in
vertebrates and invertebrates. PAX proteins are defined by the presence of a paired domain …

Homeobox genes encode sequence-specific transcription factors (SSTFs) that recognize
specific DNA sequences and regulate organogenesis in all eukaryotes. They are essential …

For more than a century, the origin and evolution of the arthropod head and brain have
eluded a unifying rationale reconciling divergent morphologies and phylogenetic …

Experience alters brain structure, but the underlying mechanism remained unknown.
Structural plasticity reveals that brain function is encoded in generative changes to cells that …

Spiders are a diverse order of chelicerates that diverged from other arthropods over 500
million years ago. Research on spider embryogenesis, particularly studies using the …

The developing eye‐antennal disc of Drosophila melanogaster has been studied for more
than a century, and it has been used as a model system to study diverse processes, such as …

Understanding how events at the molecular and cellular scales contribute to tissue form and
function is key to uncovering the mechanisms driving animal development, physiology and …

Cell death maintains tissue homeostasis by eliminating dispensable cells. Misregulation of
cell death is seen in diseases like cancer, neurodegeneration, etc. Therefore, cell death …

Size trade-offs of visual versus olfactory organs is a pervasive feature of animal evolution.
This could result from genetic or functional constraints. We demonstrate that head sensory …

Notch signaling is an evolutionarily conserved pathway which functions between adjacent
cells to establish their distinct identities. Despite operating in a simple mechanism, Notch …