Quinoline-based hybrid compounds with antimalarial activity

X Nqoro, N Tobeka, BA Aderibigbe - Molecules, 2017 - mdpi.com
The application of quinoline-based compounds for the treatment of malaria infections is
hampered by drug resistance. Drug resistance has led to the combination of quinolines with …

Combination therapy strategies for the treatment of malaria

S Alven, B Aderibigbe - Molecules, 2019 - mdpi.com
Malaria is a vector-and blood-borne infection that is responsible for a large number of
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …

Social and cultural factors affecting uptake of interventions for malaria in pregnancy in Africa: a systematic review of the qualitative research

C Pell, L Straus, EVW Andrew, A Meñaca, R Pool - PloS one, 2011 - journals.plos.org
Background Malaria during pregnancy (MiP) results in adverse birth outcomes and poor
maternal health. MiP-related morbidity and mortality is most pronounced in sub-Saharan …

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

R González, G Mombo-Ngoma, S Ouédraogo… - PLoS …, 2014 - journals.plos.org
Background Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-
pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant …

Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines

KAJ Al Khaja, RP Sequeira - Malaria journal, 2021 - Springer
Abstract Background Malaria caused by Plasmodium falciparum in pregnancy can result in
adverse maternal and fetal sequelae. This review evaluated the adherence of the national …

Malaria: an update on current chemotherapy

BJ Visser, M van Vugt, MP Grobusch - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized …

R González, M Desai, E Macete, P Ouma… - PLoS …, 2014 - journals.plos.org
Background Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-
pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant …

HIV and malaria interactions: where do we stand?

R González, R Ataíde, D Naniche… - Expert review of anti …, 2012 - Taylor & Francis
Reversing the spread of HIV infection and the incidence of malaria constitute two of the
Millenium Development Goals. However, despite recent achievements, both diseases still …

Roles of virtual screening and molecular dynamics simulations in discovering and understanding antimalarial drugs

SS Duay, RCY Yap, AL Gaitano III, JAA Santos… - International Journal of …, 2023 - mdpi.com
Malaria continues to be a global health threat, with approximately 247 million cases
worldwide. Despite therapeutic interventions being available, patient compliance is a …

Ocular toxicity in children exposed in utero to antimalarial drugs: review of the literature

A Osadchy, T Ratnapalan, G Koren - The Journal of rheumatology, 2011 - jrheum.org
Objective. The antimalarial drugs chloroquine (CQ) and hydroxychloroquine (HCQ) have
been used for decades to treat rheumatic diseases. CQ is still beneficial for the management …