[HTML][HTML] Automating drug discovery

G Schneider - Nature reviews drug discovery, 2018 - nature.com
Small-molecule drug discovery can be viewed as a challenging multidimensional problem in
which various characteristics of compounds—including efficacy, pharmacokinetics and …

Lipid-based nanoparticle technologies for liver targeting

R Böttger, G Pauli, PH Chao, NAL Fayez… - Advanced drug delivery …, 2020 - Elsevier
Liver diseases such as hepatitis, cirrhosis, and hepatocellular carcinoma are global health
problems accounting for approximately 800 million cases and over 2 million deaths per year …

Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis

Z Fattahi, M Hasanzadeh - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Microfluidics technology holds a special place in the field of biomedical and analytical
chemistry thanks to its properties, such as low consumption of reagent, quick analysis time …

Gold nanoparticles for diagnostics: advances towards points of care

M Cordeiro, F Ferreira Carlos, P Pedrosa, A Lopez… - Diagnostics, 2016 - mdpi.com
The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted
developments in the exploration of biomolecular interactions with AuNP-containing systems …

Microsized electrochemical energy storage devices and their fabrication techniques for portable applications

Z Bassyouni, A Allagui… - Advanced Materials …, 2023 - Wiley Online Library
Over the last decade, Lab‐on‐chip (LOC) technology has been thriving to support the ever‐
increasing demand of high‐throughput, fast, accurate, and reliable analysis in an extensive …

Enabling miniaturised personalised diagnostics: from lab-on-a-chip to lab-in-a-drop

KM Koo, EJH Wee, Y Wang, M Trau - Lab on a Chip, 2017 - pubs.rsc.org
The concept of personalised diagnostics is to direct accurate clinical decisions based on an
individual's unique disease molecular profile. Lab-on-a-chip (LOC) systems are prime …

Electrochemical detection of dopamine based on functionalized electrodes

M Ouellette, J Mathault, SD Niyonambaza, A Miled… - Coatings, 2019 - mdpi.com
The rapid electrochemical identification and quantification of neurotransmitters being a
challenge in the ever-growing field of neuroelectronics, we aimed to facilitate the …

Niosome: a vesicular drug delivery tool

P Patel, AK Parashar, M Kaurav, K Yadav… - Nanoparticles and …, 2022 - benthamdirect.com
Niosomes, which are well recognized for their non-ionic surfactant characteristics, are
considered to be innovative drug delivery methods since they improve the solubility and …

[HTML][HTML] Thin-film-based multifunctional system for optical detection and thermal treatment of biological samples

N Lovecchio, F Costantini, A Nascetti, G de Cesare… - Biosensors, 2022 - mdpi.com
In this work, we present a multifunctional Lab-on-Chip (LoC) platform based on
hydrogenated amorphous silicon sensors suitable for a wide range of application in the …

Phospholipid‐Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver

W Zhang, R Böttger, Z Qin, JA Kulkarni, J Vogler… - Small, 2019 - Wiley Online Library
It is reported that cholesterol (Chol) and TWEEN 80 at a molar ratio of 5: 1 can form small
unilamellar vesicles (SUVs) using a staggered herringbone micromixer. These phospholipid …