Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice

NL Diggins, AH Pham, J Mitchell, CJ Parkins, L Slind… - bioRxiv, 2024 - biorxiv.org
Human cytomegalovirus (HCMV) actively manipulates cellular signaling pathways to benefit
viral replication. Phosphatidyl-inositol 3-kinase (PI3K)/Akt signaling is an important negative …