Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

Porcine circovirus type 2 (PCV2): pathogenesis and interaction with the immune system

XJ Meng - Annu. Rev. Anim. Biosci., 2013 - annualreviews.org
Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus–
associated disease (PCVAD). The virus preferentially targets the lymphoid tissues, which …

Porcine circovirus 2 genotypes, immunity and vaccines: Multiple genotypes but one single serotype

G Franzo, J Segalés - Pathogens, 2020 - mdpi.com
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be
considered an emerging virus anymore. Nevertheless, many aspects of its biology and …

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)

NM Beach, XJ Meng - Virus research, 2012 - Elsevier
Porcine circovirus type 2 (PCV2) is the causative agent of an economically significant
collection of disease syndromes in pigs, now known as porcine circovirus associated …

Best practice and future challenges for vaccination against porcine circovirus type 2

J Segalés - Expert review of vaccines, 2015 - Taylor & Francis
Porcine circovirus type 2 (PCV2)-systemic disease (SD)(initially named as postweaning
multisystemic wasting syndrome) was discovered as an occasional disease affecting …

Porcine circovirus type 2 vaccines: commercial application and research advances

J Guo, L Hou, J Zhou, D Wang, Y Cui, X Feng, J Liu - Viruses, 2022 - mdpi.com
Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease
(PCVAD), causing great economic losses to the global swine industry. Conventional …

Ten years of PCV2 vaccines and vaccination: Is eradication a possibility?

Z Afghah, B Webb, XJ Meng, S Ramamoorthy - Veterinary microbiology, 2017 - Elsevier
More than two decades after its emergence, porcine circovirus type 2 (PCV2) remains an
economically important swine pathogen. Commercial vaccines which were first introduced to …

Porcine circovirus: transcription and DNA replication

AK Cheung - Virus research, 2012 - Elsevier
This review summarizes the molecular studies pertaining to porcine circovirus (PCV)
transcription and DNA replication. The genome of PCV is circular, single-stranded DNA and …

Current state of knowledge on porcine circovirus type 2-associated lesions

T Opriessnig, I Langohr - Veterinary pathology, 2013 - journals.sagepub.com
Porcine circovirus type 2 (PCV2), a small single-stranded DNA virus, was initially discovered
in 1998 and is highly prevalent in the domestic pig population. Disease manifestations …

Emerging and re‐emerging swine viruses

XJ Meng - Transboundary and emerging diseases, 2012 - Wiley Online Library
In the past two decades or so, a number of viruses have emerged in the global swine
population. Some, such as porcine reproductive and respiratory syndrome virus (PRRSV) …