The pharmacological bases for repurposing statins in depression: a review of mechanistic studies
Statins are commonly prescribed medications widely investigated for their potential actions
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …
[HTML][HTML] The effects of statin monotherapy on depressive symptoms: A systematic review and meta-analysis
R De Giorgi, S Waters, NR Pesci, G Rosso… - Journal of Affective …, 2022 - Elsevier
Introduction Statins have been proposed as a strategy for treating depression, but their
benefit in the absence of concurrent antidepressant treatment is unclear. This meta-analysis …
benefit in the absence of concurrent antidepressant treatment is unclear. This meta-analysis …
The effects of atorvastatin on emotional processing, reward learning, verbal memory and inflammation in healthy volunteers: an experimental medicine study
R De Giorgi, M Martens, N Rizzo Pesci… - Journal of …, 2021 - journals.sagepub.com
Background: Growing evidence from clinical trials and epidemiological studies suggests that
statins can have clinically significant antidepressant effects, potentially related to anti …
statins can have clinically significant antidepressant effects, potentially related to anti …
An online experimental medicine trial on the effect of 28-day simvastatin administration on emotional processing, reward learning, working memory and salivary …
S Waters, R De Giorgi, AMG Quinton, AL Gillespie… - BJPsych Open, 2023 - cambridge.org
BackgroundEvidence suggests inflammation may be a key mechanism by which
psychosocial stress, including loneliness, predisposes to depression. Observational and …
psychosocial stress, including loneliness, predisposes to depression. Observational and …
An online experimental medicine trial on the effect of 28-day simvastatin administration on emotional processing, reward learning, working memory and salivary …
R Di Giorgi, PJ Cowen - 2023 - oxfordhealth-nhs.archive …
Background: Evidence suggests inflammation may be a key mechanism by which
psychosocial stress, including loneliness, predisposes to depression. Observational and …
psychosocial stress, including loneliness, predisposes to depression. Observational and …