Kléber, André G., and Yoram Rudy. Basic Mechanisms of Cardiac Impulse Propagation and
Associated Arrhythmias. Physiol Rev 84: 431–488, 2004; 10.1152/physrev. 00025.2003 …

Abstract Moorman, Antoon FM, and Vincent M. Christoffels. Cardiac Chamber Formation:
Development, Genes, and Evolution. Physiol Rev 83: 1223-1267, 2003; 10.1152/physrev …

Gap junctions play a pivotal role for the velocity and the safety of impulse propagation in
cardiac tissue. Under physiologic conditions, the specific subcellular distribution of gap …

The cardiac sodium channel NaV1. 5, encoded by the SCN5A gene, is responsible for the
fast upstroke of the action potential. Mutations in SCN5A may cause sodium channel …

The epicardial border zone (EBZ) of canine infarcts has increased anisotropy because of
transverse conduction slowing. It remains unknown whether changes in gap junctional …

The role of gap junction channels on cardiac impulse propagation is complex. This review
focuses on the differential expression of connexins in the heart and the biophysical …

Anisotropy, the property of being directionally dependent, is ubiquitous in nature.
Propagation of the electrical impulse in cardiac tissue is anisotropic, a property that is …

Background: The epicardial border zone (EBZ) of surviving myocytes in the healing, 4-to 5-
day-old canine infarct is an arrhythmogenic substrate characterized by both structural and …

Background This review comes after the International Gap Junction Conference (IGJC 2015)
and describes the current knowledge on the function of the specific motifs of connexins in …

To characterize the role of connexin43 (Cx43) as a determinant of cardiac propagation, we
synthesized strands and pairs of ventricular myocytes from germline Cx43−/− mice. The …