Engineering synthetic biomolecular condensates

Y Dai, L You, A Chilkoti - Nature Reviews Bioengineering, 2023 - nature.com
The concept of phase-separation-mediated formation of biomolecular condensates provides
a new framework to understand cellular organization and cooperativity-dependent cellular …

Strategies for making high‐performance artificial spider silk fibers

B Schmuck, G Greco, TB Pessatti… - Advanced Functional …, 2024 - Wiley Online Library
Artificial spider silk is an attractive material for many technical applications since it is a
biobased fiber that can be produced under ambient conditions but still outcompetes …

[HTML][HTML] Charge-reversible and biodegradable chitosan-based microgels for lysozyme-triggered release of vancomycin

X Li, L Hetjens, N Wolter, H Li, X Shi, A Pich - Journal of advanced research, 2023 - Elsevier
Introduction High-dose drug administration for the conventional treatment of inflammatory
bowel disease induces cumulative toxicity and serious side effects. Currently, few reports …

Granular hydrogels: emergent properties of jammed hydrogel microparticles and their applications in tissue repair and regeneration

L Riley, L Schirmer, T Segura - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Jamming phenomenon in granular hydrogels enables microporosity and
injectability.•Heterogeneous combinations of microgels produce complex, multifunctional …

Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis

DM Shapiro, G Mandava, SE Yalcin… - Nature …, 2022 - nature.com
Advances in synthetic biology permit the genetic encoding of synthetic chemistries at
monomeric precision, enabling the synthesis of programmable proteins with tunable …

Microfluidic synthesis control technology and its application in drug delivery, bioimaging, biosensing, environmental analysis and cell analysis

CT Kung, H Gao, CY Lee, YN Wang, W Dong… - Chemical Engineering …, 2020 - Elsevier
Nanomaterials have attracted significant attention in biomedical and environmental science
in recent years due to their unique thermal, optical, electrical and magnetic properties. The …

Recombinant protein-based injectable materials for biomedical applications

CG Garcia, SS Patkar, B Wang, R Abouomar… - Advanced Drug Delivery …, 2023 - Elsevier
Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

Different strategies for organic nanoparticle preparation in biomedicine

F Fang, M Li, J Zhang, CS Lee - ACS Materials Letters, 2020 - ACS Publications
Organic nanoparticles with intriguing features have attracted widespread attention for
various biomedical applications, such as disease diagnosis, drug delivery, bioimaging, and …

Microfluidics fabrication of micrometer‐sized hydrogels with precisely controlled geometries for biomedical applications

Z Wei, S Wang, J Hirvonen… - Advanced healthcare …, 2022 - Wiley Online Library
Micrometer‐sized hydrogels are cross‐linked three‐dimensional network matrices with high‐
water contents and dimensions ranging from several to hundreds of micrometers. Due to …

Unnatural amino acids: production and biotechnological potential

T Narancic, SA Almahboub, KE O'Connor - World Journal of Microbiology …, 2019 - Springer
Unnatural amino acids (UAAs) are valuable building blocks in the manufacture of a wide
range of pharmaceuticals. UAAs exhibit biological activity as free acids and they can be …