Evolution of pathogen tolerance and emerging infections: A missing experimental paradigm
S Seal, G Dharmarajan, I Khan - Elife, 2021 - elifesciences.org
Researchers worldwide are repeatedly warning us against future zoonotic diseases
resulting from humankind's insurgence into natural ecosystems. The same zoonotic …
resulting from humankind's insurgence into natural ecosystems. The same zoonotic …
Common themes in zoonotic spillover and disease emergence: Lessons learned from bat-and rodent-borne RNA viruses
EP Williams, BM Spruill-Harrell, MK Taylor, J Lee… - Viruses, 2021 - mdpi.com
Rodents (order Rodentia), followed by bats (order Chiroptera), comprise the largest
percentage of living mammals on earth. Thus, it is not surprising that these two orders …
percentage of living mammals on earth. Thus, it is not surprising that these two orders …
Strengthening a One Health approach to emerging zoonoses
Given the enormous global impact of the COVID-19 pandemic, outbreaks of highly
pathogenic avian influenza in Canada, and manifold other zoonotic pathogen activity, there …
pathogenic avian influenza in Canada, and manifold other zoonotic pathogen activity, there …
Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea
Bats are reservoir hosts of many zoonotic viruses with pandemic potential. We utilized single-
cell transcriptome sequencing (scRNA-seq) to analyze the immune response in bat lungs …
cell transcriptome sequencing (scRNA-seq) to analyze the immune response in bat lungs …
Landscape and age dynamics of immune cells in the Egyptian rousette bat
V Friedrichs, C Toussaint, A Schäfer, M Rissmann… - Cell Reports, 2022 - cell.com
Bats harbor high-impact zoonotic viruses often in the absence of disease manifestation. This
restriction and disease tolerance possibly rely on specific immunological features. In-depth …
restriction and disease tolerance possibly rely on specific immunological features. In-depth …
Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats
SA Riesle-Sbarbaro, G Wibbelt, A Düx… - Nature …, 2024 - nature.com
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African
countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology …
countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology …
Marburg virus persistence on fruit as a plausible route of bat to primate filovirus transmission
Marburg virus (MARV), the causative agent of Marburg virus disease, emerges sporadically
in sub-Saharan Africa and is often fatal in humas. The natural reservoir for this zoonotic virus …
in sub-Saharan Africa and is often fatal in humas. The natural reservoir for this zoonotic virus …
Comparative analyses of bat genomes identify distinct evolution of immunity in Old World fruit bats
Bats have been identified as natural reservoir hosts of several zoonotic viruses, prompting
suggestions that they have unique immunological adaptations. Among bats, Old World fruit …
suggestions that they have unique immunological adaptations. Among bats, Old World fruit …
Robust evidence for bats as reservoir hosts is lacking in most African virus studies: a review and call to optimize sampling and conserve bats
Africa experiences frequent emerging disease outbreaks among humans, with bats often
proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings …
proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings …
Future trends in measuring physiology in free-living animals
Thus far, ecophysiology research has predominantly been conducted within controlled
laboratory-based environments, owing to a mismatch between the recording technologies …
laboratory-based environments, owing to a mismatch between the recording technologies …