Latency is a state of cryptic viral infection associated with genomic persistence and highly
restricted gene expression. Its hallmark is reversibility: under appropriate circumstances …

SUMMARY Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated
herpesvirus (KSHV), discovered in 1994, is a human rhadinovirus (gamma-2 herpesvirus) …

Productive herpesvirus infection requires a profound, time-controlled remodeling of the viral
transcriptome and proteome. To gain insights into the genomic architecture and gene …

Abstract Human herpesvirus-8 (HHV-8) is implicated in the pathogenesis of Kaposi's
sarcoma. HHV-8 envelope glycoprotein B possesses the RGD motif known to interact with …

Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) is closely associated with
Kaposi's sarcoma (KS) and primary effusion lymphoma, with viral genomes present in a …

A hallmark of all herpesvirus is the ability to exist in either a latent, or lytic, state of
replication, enabling the lifelong infection of its host. Kaposi's sarcoma (KS)-associated …

To replicate their genomes in cells and generate new progeny, viruses typically require
factors provided by the cells that they have infected. Subversion of the cellular machinery …

Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is linked to KS, primary effusion
lymphomas (PEL), and a subset of multicentric Castleman's disease (MCD). Transcript …

Kaposi sarcoma–associated (KS-associated) herpesvirus (KSHV) infection is linked to the
development of both KS and several lymphoproliferative diseases. In all cases, the resulting …

Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …