[HTML][HTML] DNA and histone methylation in gastric carcinogenesis
Epigenetic alterations contribute significantly to the development and progression of gastric
cancer, one of the leading causes of cancer death worldwide. Epigenetics refers to the …
cancer, one of the leading causes of cancer death worldwide. Epigenetics refers to the …
Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation
Z Herceg, MP Lambert, K van Veldhoven… - …, 2013 - academic.oup.com
Remarkable progress in the field of epigenetics has turned academic, medical and public
attention to the potential applications of these new advances in medicine and various fields …
attention to the potential applications of these new advances in medicine and various fields …
[HTML][HTML] Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense
J Jantsch, V Schatz, D Friedrich, A Schröder, C Kopp… - Cell metabolism, 2015 - cell.com
Immune cells regulate a hypertonic microenvironment in the skin; however, the biological
advantage of increased skin Na+ concentrations is unknown. We found that Na+ …
advantage of increased skin Na+ concentrations is unknown. We found that Na+ …
Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine
M Stein, P Ruggiero, R Rappuoli, F Bagnoli - Frontiers in immunology, 2013 - frontiersin.org
Helicobacter pylori colonizes the gastric mucosa of more than 50% of the human population,
causing chronic inflammation, which however is largely asymptomatic. Nevertheless, H …
causing chronic inflammation, which however is largely asymptomatic. Nevertheless, H …
The immune battle against Helicobacter pylori infection: NO offense
Helicobacter pylori is a successful pathogen of the human stomach. Despite a vigorous
immune response by the gastric mucosa, the bacterium survives in its ecological niche, thus …
immune response by the gastric mucosa, the bacterium survives in its ecological niche, thus …
LPS-induced histone H3 phospho (Ser10)-acetylation (Lys14) regulates neuronal and microglial neuroinflammatory response
Epigenetic modifications of DNA and histone proteins are emerging as fundamental
mechanisms by which neural cells adapt their transcriptional response to environmental …
mechanisms by which neural cells adapt their transcriptional response to environmental …
Host Cell Antimicrobial Responses against Helicobacter pylori Infection: From Biological Aspects to Therapeutic Strategies
The colonization of Helicobacter pylori (H. pylori) in human gastric mucosa is highly
associated with the occurrence of gastritis, peptic ulcer, and gastric cancer. Antibiotics …
associated with the occurrence of gastritis, peptic ulcer, and gastric cancer. Antibiotics …
The enterochromaffin-like [ECL] cell—Central in gastric physiology and pathology
HL Waldum, ØF Sørdal, PG Mjønes - International Journal of Molecular …, 2019 - mdpi.com
Background: Studies on the regulation of gastric and pancreatic secretion began more than
100 years ago. Secretin was the first hormone postulated to exist, initiating the field of …
100 years ago. Secretin was the first hormone postulated to exist, initiating the field of …
Influences of lysine‐specific demethylase 1 inhibitors on NO synthase–Kruppel‐like factor pathways in human endothelial cells in vitro and zebrafish (Danio rerio) …
J Yuan, R Que, W Zhao, F Song… - Journal of Applied …, 2023 - Wiley Online Library
Abstract Lysine‐specific demethylase 1 (LSD1) inhibitors are being developed for cancer
therapy, but their bioeffects on vasculatures are not clear. In this study, we compared the …
therapy, but their bioeffects on vasculatures are not clear. In this study, we compared the …
Linking immunity, epigenetics, and cancer in inflammatory bowel disease
J Däbritz, TR Menheniott - Inflammatory bowel diseases, 2014 - academic.oup.com
Most of what is known about the pathogenesis of inflammatory bowel disease (IBD) pertains
to complex interplay between host genetics, immunity, and environmental factors. Epigenetic …
to complex interplay between host genetics, immunity, and environmental factors. Epigenetic …