Factors that influence the immune response to vaccination

P Zimmermann, N Curtis - Clinical microbiology reviews, 2019 - Am Soc Microbiol
There is substantial variation between individuals in the immune response to vaccination. In
this review, we provide an overview of the plethora of studies that have investigated factors …

The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

Significant correlation between the infant gut microbiome and rotavirus vaccine response in rural Ghana

VC Harris, G Armah, S Fuentes… - The Journal of …, 2017 - academic.oup.com
Background Rotavirus (RV) is the leading cause of diarrhea-related death in children
worldwide and 95% of RV-associated deaths occur in Africa and Asia where RV vaccines …

Causes of impaired oral vaccine efficacy in developing countries

EPK Parker, S Ramani, BA Lopman, JA Church… - Future …, 2018 - Taylor & Francis
Oral vaccines are less immunogenic when given to infants in low-income compared with
high-income countries, limiting their potential public health impact. Here, we review factors …

Immunity to enteric viruses

A Lockhart, D Mucida, R Parsa - Immunity, 2022 - cell.com
Pathogenic enteric viruses are a major cause of morbidity and mortality, particularly among
children in developing countries. The host response to enteric viruses occurs primarily within …

Immunological factors linked to geographical variation in vaccine responses

MMAR van Dorst, JJ Pyuza, G Nkurunungi… - Nature Reviews …, 2024 - nature.com
Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …

Rotavirus vaccine response correlates with the infant gut microbiota composition in Pakistan

V Harris, A Ali, S Fuentes, K Korpela, M Kazi, J Tate… - Gut …, 2018 - Taylor & Francis
Rotavirus (RV) is the leading cause of diarrhea-related death in children worldwide and
ninety-five percent of rotavirus deaths occur in Africa and Asia. Rotavirus vaccines (RVV) …

The influence of the intestinal microbiome on vaccine responses

P Zimmermann, N Curtis - Vaccine, 2018 - Elsevier
There is substantial variation between individuals in the immune response to vaccinations.
The intestinal microbiome plays a crucial rule in the development and regulation of the …

Differences of rotavirus vaccine effectiveness by country: likely causes and contributing factors

U Desselberger - Pathogens, 2017 - mdpi.com
Rotaviruses are a major cause of acute gastroenteritis in infants and young children
worldwide and in many other mammalian and avian host species. Since 2006, two live …

Understanding rotavirus vaccine efficacy and effectiveness in countries with high child mortality

T Varghese, G Kang, AD Steele - Vaccines, 2022 - mdpi.com
Rotavirus claims thousands of lives of children globally every year with a disproportionately
high burden in low-and lower-middle income countries where access to health care is …