The size and/or configuration of the cycloalkane D′ ring in pentacyclic progesterone derivatives are crucial for their high-affinity binding to a protein in addition to …
AN Smirnov, EV Pokrovskaya, GS Kogteva… - Steroids, 2000 - Elsevier
[3H] labeled progesterone and a number of its 16α, 17α-cycloalkano derivatives with an
additional three to six-membered D′ ring were investigated for mutual competition and …
additional three to six-membered D′ ring were investigated for mutual competition and …
Pregna-D′-pentarane structure influences progesterone receptor affinity for DNA
TA Shchelkunova, PM Rubtsov, IS Levina… - Steroids, 2002 - Elsevier
Electrophoretic mobility shift assay was used to determine whether pregna-D′-pentaranes
allow progesterone receptor (PR) from rat uterine cytosol to bind hormone response element …
allow progesterone receptor (PR) from rat uterine cytosol to bind hormone response element …
Species and tissue distribution of proteins binding 16α, 17α-cycloalkanoprogesterone derivatives
AN Smirnov, EV Pokrovskaya, VP Shevchenko… - Russian Journal of …, 2002 - Springer
The binding of [3 H] progesterone and [3 H] 16α, 17α-cycloalkanoprogesterones to proteins
from rat, rabbit, and human uteri and other organs was studied. We found that 16α, 17α …
from rat, rabbit, and human uteri and other organs was studied. We found that 16α, 17α …
[PDF][PDF] ВИДОВЫЕ И ТКАНЕВЫЕ ОСОБЕННОСТИ РАСПРЕДЕЛЕНИЯ БЕЛКОВ, СВЯЗЫВАЮЩИХ 16or, 17o-ЦИКЛОАЛКАНОВЫЕ ПРОИЗВОДНЫЕ …
НФ Мясоедов, ИС Левина, ЛЕ Куликова… - Биоорганическая …, 2002 - rjbc.ru
Исследовано связывание [3Н] прогестерона и 3Н-меченых 16а, 17ос-
циклоалканопрогестеронов с белками матки и других органов крысы, кролика и …
циклоалканопрогестеронов с белками матки и других органов крысы, кролика и …
Conformational analysis of 20-keto steroids. Single-crystal X-ray structure analysis of 16α, 17-epoxy-4-pregnene-3, 20-dione
K Goubitz, H Schenk, FJ Zeelen - Steroids, 1984 - Elsevier
3289 153 Volume 44, Number 2 S ~ ma ~ ox ~ m August 1984 Page 1 3289 153
CONFORMATIONAL ANALYSIS OF 20-KETO STEROIDS. SINGLE-CRYSTAL X-RAY …
CONFORMATIONAL ANALYSIS OF 20-KETO STEROIDS. SINGLE-CRYSTAL X-RAY …
The synthesis of 5-methyl-19-nor-5β-pregna-9, 16-diene-3, 20-dione, 5-methyl-19-nor-5β-pregna-9, 10-diene-3, 6, 20-trione and their analogues with annellated E …
J Polman, A Kasal - Collection of Czechoslovak chemical …, 1991 - cccc.uochb.cas.cz
The synthesis of compounds VII, XVII, XXXIV and XXXVII is described, in which biological
activity is assumed. The key steps of their preparation are the dehalogenation of compound …
activity is assumed. The key steps of their preparation are the dehalogenation of compound …
ПЕНТАЦИКЛИЧЕСКИЕ АНАЛОГИ СТЕРОИДОВ: ВЗАИМОДЕЙСТВИЕ 16а, 17а-ЦИКЛОПЕНТАНОПРОГЕСТЕРОНА С БЕЛКАМИ МАТКИ КРЫСЫ
АН Смирнов, ЕВ Покровская, ВП Шевченко… - Биоорганическая …, 1999 - elibrary.ru
С помощью 3 Н-меченых производных измерены кинетические параметры
специфического связывания прогестерона (I) и 16а, 17а-циклопентанопрогеетерона (II) …
специфического связывания прогестерона (I) и 16а, 17а-циклопентанопрогеетерона (II) …
The Synthesis of O-Substituted 6-Oximes of 16α,17α-Cyclohexanopregn-4-ene-3,6,20-trione Labeled by Tritium in Position 1,2
VP Shevchenko, IY Nagaev, NF Myasoedov… - Russian Journal of …, 2002 - Springer
O-(3-Methoxycarbonylpropyl)-and 6-O-(3-carboxypropyl) oximes of 16α, 17α-
cyclohexanopregn-4-ene-3, 6, 20-trione labeled by tritium in position 1, 2 were synthesized …
cyclohexanopregn-4-ene-3, 6, 20-trione labeled by tritium in position 1, 2 were synthesized …
16α, 17α-Cycloalkane Derivatives of Progesterone Intensively Bind to a Rat Serum Protein
AN Smirnov, EV Pokrovskaya, IS Levina… - Biochemistry …, 2001 - Springer
The interaction of 6α-methyl-[1, 2-3 H] 16α, 17α-cyclohexanoprogesterone with rat serum
proteins has been studied. Specific binding of this ligand characterized by K d= 0.36±0.10 …
proteins has been studied. Specific binding of this ligand characterized by K d= 0.36±0.10 …
Physiologically active substances PF1092A, PF1092B and PF1092C, process for the production thereof, and contraceptives and anticancer drugs containing the same …
Y Tabata, M Hatsu, N Miike, T Yaguchi… - US Patent …, 1998 - Google Patents
In view of the above, the present inventors have continued screening of substances which
inhibit binding of progester one to progesterone receptor and have found that substances …
inhibit binding of progester one to progesterone receptor and have found that substances …