This article reviews currently used approaches for establishing dose proportionality in Phase
I dose escalation studies. A review of relevant literature between 2002 and 2006 found that …

Bioequivalence studies are performed to demonstrate in vivo that two pharmaceutically
equivalent products (in the US) or alternative pharmaceutical products (in the EU) are …

The first edition of Design and Analysis of Cross-Over Trials quickly became the standard
reference on the subject and has remained so for more than 12 years. In that time, however …

Equivalence testing has grown significantly in importance over the last two decades,
especially as its relevance to a variety of applications has become understood. Yet …

A modern and comprehensive treatment of tolerance intervals and regions The topic of
tolerance intervals and tolerance regions has undergone significant growth during recent …

Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition
focuses on the statistical aspects ofmedicine with a medical perspective, showing the utility …

The study aim was to objectively compare learning outcomes of two pedagogies as
measured quantitatively through exam questions, quiz scores, and course grades. Eighty …

Statement of problem Mandibular implant overdentures provide improved treatment
outcome than conventional denture therapy, but there is controversy as to which …

After several drugs were removed from the market in recent years because of death due to
ventricular tachycardia resulting from drug-induced QT prolongation (Khongphatthanayothin …

Highlights•Although understudied, recent studies suggest that female birdsong is
widespread.•We compared male and female song using a novel statistical equivalence …