Diversity and versatility of p38 kinase signalling in health and disease
B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
The ability of cells to deal with different types of stressful situations in a precise and
coordinated manner is key for survival and involves various signalling networks. Over the …
coordinated manner is key for survival and involves various signalling networks. Over the …
Toxoplasma Effectors Targeting Host Signaling and Transcription
Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
The pathogenicity and virulence of Toxoplasma gondii
SG Sanchez, S Besteiro - Virulence, 2021 - Taylor & Francis
Toxoplasma gondii is a parasitic protist infecting a wide group of warm-blooded animals,
ranging from birds to humans. While this infection is usually asymptomatic in healthy …
ranging from birds to humans. While this infection is usually asymptomatic in healthy …
The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment
Signal transducer and activator of transcription (STAT) proteins communicate from cell-
surface receptors to drive transcription of immune response genes. The parasite …
surface receptors to drive transcription of immune response genes. The parasite …
Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii
Toxoplasma gondii is an obligate intracellular parasite that can infect virtually all nucleated
cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and …
cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and …
Toxoplasma gondii Modulates the Host Cell Responses: An Overview of Apoptosis Pathways
N Mammari, MA Halabi, S Yaacoub… - BioMed research …, 2019 - Wiley Online Library
Infection with Toxoplasma gondii has a major implication in public health. Toxoplasma
gondii is an obligate intracellular protozoan parasite that can infect all nucleated cells …
gondii is an obligate intracellular protozoan parasite that can infect all nucleated cells …
Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity
HL Mercer, LM Snyder, CM Doherty, BA Fox… - PLoS …, 2020 - journals.plos.org
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon
recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in …
recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in …
Toxoplasma Mechanisms for Delivery of Proteins and Uptake of Nutrients Across the Host-Pathogen Interface
Y Wang, LO Sangaré… - Annual review of …, 2020 - annualreviews.org
Many intracellular pathogens, including the protozoan parasite Toxoplasma gondii, live
inside a vacuole that resides in the host cytosol. Vacuolar residence provides these …
inside a vacuole that resides in the host cytosol. Vacuolar residence provides these …
Transport mechanisms at the malaria parasite-host cell interface
Obligate intracellular malaria parasites reside within a vacuolar compartment generated
during invasion which is the principal interface between pathogen and host. To subvert their …
during invasion which is the principal interface between pathogen and host. To subvert their …
Seizing control: How dense granule effector proteins enable Toxoplasma to take charge
MW Panas, JC Boothroyd - Molecular microbiology, 2021 - Wiley Online Library
Control of the host cell is crucial to the Apicomplexan parasite, Toxoplasma gondii, while it
grows intracellularly. To achieve this goal, these single‐celled eukaryotes export a series of …
grows intracellularly. To achieve this goal, these single‐celled eukaryotes export a series of …