Quercetin, a natural flavonoid compound with a widespread occurrence throughout the plant
kingdom, exhibits a variety of pharmacological activities. Because of the wide spectrum of …

This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …

Background Liver fibrosis (LF) is a trauma repair process carried out by the liver in response
to various acute and chronic liver injuries. Its primary pathological characteristics are …

Background Quercetin (QC) is a naturally occurring flavonoid found in abundance in fruits
and vegetables. Its anti-cancer and anti-inflammatory properties have been previously …

Liver diseases emerge as a serious threat to humans worldwide due to increasing morbidity
and mortality. Liver disease related deaths accounts for one third of all disease related death …

Objective (s): Non-alcoholic fatty liver disease (NAFLD) is the most common liver-related
metabolic disorder in the world, with a global prevalence of 25%. Compounds with anti …

Background: Hepatic fibrosis is characterized by the increased proliferation and activation of
hepatic stellate cells. Transforming growth factor-beta (TGF-β) stimulates these stellate cells …

Background: Activated hepatic stellate cells (HSC) through the TGF-β signaling pathway are
likely to exacerbate liver fibrosis, which is a later stage of NASH, a condition in which, in …

Objective (s): Non-alcoholic fatty liver disease (NAFLD) is a chronic steatohepatitis disorder.
If left untreated, it can progress to hepatocellular carcinoma. Several studies have shown …