[HTML][HTML] Biologics, theranostics, and personalized medicine in drug delivery systems

M Puccetti, M Pariano, A Schoubben… - Pharmacological …, 2024 - Elsevier
The progress in human disease treatment can be greatly advanced through the
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …

PLGA nanomedical consignation: a novel approach for the management of prostate cancer

TS Dongsar, TT Dongsar, G Gupta, A Alsayari… - International Journal of …, 2024 - Elsevier
The malignancy of the prostate is a complicated ailment which impacts millions of male
populations around the globe. Despite the multitude of endeavour accomplished within this …

Liposome Nanocarriers Based on γ Oryzanol: Preparation, Characterization, and In Vivo Assessment of Toxicity and Antioxidant Activity

AJ Jasim, S Albukhaty, GM Sulaiman, H Al-Karagoly… - ACS …, 2024 - ACS Publications
The present study aimed to develop and characterize liposome nanocarriers based on γ
oryzanol and evaluate their potential in vitro and in vivo toxicity and antioxidant effects. The …

αvβ3 integrin targeting RGD peptide-based nanoparticles as an effective strategy for selective drug delivery to tumor microenvironment

P Kesharwani, J Chandra, S Karim, G Gupta… - Journal of Drug Delivery …, 2024 - Elsevier
Integrin αvβ3 is crucial in the process of angiogenesis, present in both tumoral endothelium
cells and some tumor cells. Most RGD peptides have a strong affinity for the αvβ3 integrin …

Scouting the efficacy of targeted gold nanoparticles in the landscape of cancer therapy

M Fatima, G Gupta, SJ Arora, A Alsayari… - European Polymer …, 2024 - Elsevier
Treating a grievous disease like cancer requires a highly effective, non-intrusive therapy
with minimum associated complications. Gold nanoparticles have been a pioneer in …

Intracellular Trafficking of Size-Tuned Nanoparticles for Drug Delivery

S Gimondi, H Ferreira, RL Reis, NM Neves - International Journal of …, 2023 - mdpi.com
Polymeric nanoparticles (NPs) are widely used as drug delivery systems in nanomedicine.
Despite their widespread application, a comprehensive understanding of their intracellular …

Targeted Nanoparticle-Based Diagnostic and Treatment Options for Pancreatic Cancer

X Gu, T Minko - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) accounts for 90% of pancreatic
cancers. It is considered one of the deadliest cancers due to its high metastatic potential and …

A review on lipid-polymer hybrid nanocarriers in cancer

D Karati, S Mukherjee, B Prajapati, A Bose… - Journal of Drug Delivery …, 2024 - Elsevier
Cancer continues to be a leading cause of death and presents a variety of treatment-related
problems, including chemoresistance, toxicity, etc. Since nanoformulations provide …

Chitosan: An overview of biological activities, derivatives, properties, and current advancements in biomedical applications.

GI Edo, E Yousif, MH Al-Mashhadani - Carbohydrate Research, 2024 - Elsevier
The second and most often utilized natural polymer is chitosan (CS), a naturally existing
amino polysaccharide that is produced by deacetylating chitin. Numerous applications have …

Nanoparticles for efficient drug delivery and drug resistance in glioma: New perspectives

J Liu, F Yang, J Hu, X Zhang - CNS Neuroscience & …, 2024 - Wiley Online Library
Gliomas are the most common primary tumors of the central nervous system, with
glioblastoma multiforme (GBM) having the highest incidence, and their therapeutic efficacy …