[HTML][HTML] Cutting, amplifying, and aligning microtubules with severing enzymes

YW Kuo, J Howard - Trends in cell biology, 2021 - cell.com
Microtubule-severing enzymes–katanin, spastin, fidgetin–are related AAA-ATPases that cut
microtubules into shorter filaments. These proteins, also called severases, are involved in a …

[HTML][HTML] Molecular and cellular mechanisms of spastin in neural development and disease

Q Liu, G Zhang, Z Ji, H Lin - … journal of molecular …, 2021 - spandidos-publications.com
Spastin is a microtubule (MT)‑severing enzyme identified from mutations of hereditary
spastic paraplegia in 1999 and extensive studies indicate its vital role in various cellular …

Microtubule nucleation complex behavior is critical for cortical array homogeneity and xylem wall patterning

B Jacobs, R Schneider, J Molenaar… - Proceedings of the …, 2022 - National Acad Sciences
Plant cell walls are versatile materials that can adopt a wide range of mechanical properties
through controlled deposition of cellulose fibrils. Wall integrity requires a sufficiently …

[HTML][HTML] Microtubule simulations in plant biology: A field coming to maturity

M Saltini, EE Deinum - Current Opinion in Plant Biology, 2024 - Elsevier
The plant cortical microtubule array is an important determinant of cell wall structure and,
therefore, plant morphology and physiology. The array consists of dynamic microtubules …

A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation

M Saltini, BM Mulder - Quantitative Plant Biology, 2021 - cambridge.org
The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis
thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule …

Computer simulation reveals the effect of severing enzymes on dynamic and stabilized microtubules

A Sen, A Kunwar - Physical Biology, 2023 - iopscience.iop.org
Microtubule (MT) severing enzymes Katanin and Spastin cut the MT into smaller fragments
and are being studied extensively using in-vitro experiments due to their crucial role in …

The force required to remove tubulin from the microtubule lattice

YW Kuo, M Mahamdeh, Y Tuna, J Howard - bioRxiv, 2022 - biorxiv.org
Severing enzymes and molecular motors extract tubulin from the walls of microtubules by
exerting mechanical force on subunits buried in the lattice. However, how much force is …

Exploring mechanisms of xylem cell wall patterning with dynamic models

B Jacobs - 2022 - search.proquest.com
Vascular plants employ an extensive vascular system, known as the xylem, to transport
water from their roots to their leaves. Xylem vessels possess thick secondary cell walls that …

Nucleation complex behaviour is critical for cortical microtubule array homogeneity and patterning

B Jacobs, R Schneider, J Molenaar, L Filion… - bioRxiv, 2022 - biorxiv.org
Plant cell walls are versatile materials that can adopt a wide range of mechanical properties
through controlled deposition of cellulose fibrils. Wall integrity requires a sufficiently …

A plausible mechanism for longitudinal lock-in of cortical microtubule array after light-induced reorientation

M Saltini, BM Mulder - bioRxiv, 2020 - biorxiv.org
The light-induced reorientation of the cortical microtubule array in dark-grown A. thaliana
hypocotyl cells is a striking example of the dynamical plasticity of the microtubule …