Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Non-alcoholic fatty liver disease—the most common chronic liver disease—encompasses a
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …

Galectin-3 is a versatile protein orchestrating several physiological and pathophysiological
processes in the human body. In the last decade, considerable interest in galectin-3 has …

In obesity, macrophages and other immune cells accumulate in insulin target tissues,
promoting a chronic inflammatory state and insulin resistance. Galectin-3 (Gal3), a lectin …

How the carbohydrate binding protein galectin-3 might act as a diabetogenic and
tumorogenic factor remains to be investigated. Here we report that intracellular galectin-3 …

Chronic kidney disease (CKD) is a risk factor for end-stage renal disease (ESRD) and
cardiovascular disease (CVD). ESRD or CVD develop in a substantial proportion of patients …

Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Circulating levels of adiponectin (APN) are reduced in obesity and associated comorbidities,
with inflammation playing an important role in downregulating APN production. In contrast to …

The gut microbiome plays an important role in health and disease. Antibiotics are known to
alter gut microbiota, yet their effects on glucose tolerance in lean, normoglycemic mice have …

Krüppel-like factors (KLFs) are deoxyribonucleic acid–binding transcriptional factors that
regulate various pathways that control metabolism and other cellular mechanisms. Various …