Radioactive transition metals for imaging and therapy
E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …
emission tomography (PET) and single-photon imaging, including single-photon emission …
Current advances in ligand design for inorganic positron emission tomography tracers 68 Ga, 64 Cu, 89 Zr and 44 Sc
TW Price, J Greenman, GJ Stasiuk - Dalton transactions, 2016 - pubs.rsc.org
A key part of the development of metal based Positron Emission Tomography probes is the
chelation of the radiometal. In this review the recent developments in the chelation of four …
chelation of the radiometal. In this review the recent developments in the chelation of four …
Red blood cell‐facilitated photodynamic therapy for cancer treatment
Photodynamic therapy (PDT) is a promising treatment modality for cancer management. So
far, most PDT studies have focused on delivery of photosensitizers to tumors. O2, another …
far, most PDT studies have focused on delivery of photosensitizers to tumors. O2, another …
Copper radiopharmaceuticals for theranostic applications
A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …
different fields to integrate imaging and therapeutic modalities in a theranostic …
Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation
LE McInnes, SE Rudd, PS Donnelly - Coordination Chemistry Reviews, 2017 - Elsevier
Positron emission tomography (PET) is a medical diagnostic imaging technique that
requires administration of a β+-emitting radiotracer to a patient. Metal-based PET …
requires administration of a β+-emitting radiotracer to a patient. Metal-based PET …
H2CHXdedpa and H4CHXoctapaChiral Acyclic Chelating Ligands for 67/68Ga and 111In Radiopharmaceuticals
The chiral acyclic ligands H2 CHX dedpa (N4O2), H2 CHX dedpa-bb (N4O2), and H4 CHX
octapa (N4O4)(CHX= cyclohexyl/cyclohexane, H2dedpa= 1, 2-[[6-carboxy-pyridin-2-yl] …
octapa (N4O4)(CHX= cyclohexyl/cyclohexane, H2dedpa= 1, 2-[[6-carboxy-pyridin-2-yl] …
Radiometals: towards a new success story in nuclear imaging?
D Brasse, A Nonat - Dalton Transactions, 2015 - pubs.rsc.org
Several limitations of 18F and other non-metallic isotopes have been emphasized by the
development of macromolecular biotargeting agents for cancer, including peptides …
development of macromolecular biotargeting agents for cancer, including peptides …
When ring makes the difference: coordination properties of Cu 2+/Cu+ complexes with sulfur-pendant polyazamacrocycles for radiopharmaceutical applications
Three polyazamacrocyclic ligands, ie 1, 5, 9-tris [2-(methylsulfanyl) ethyl]-1, 5, 9-
triazacyclododecane (TACD3S), 1, 4, 7, 10-tetrakis [2-(methylsulfanyl) ethyl]-1, 4, 7, 10 …
triazacyclododecane (TACD3S), 1, 4, 7, 10-tetrakis [2-(methylsulfanyl) ethyl]-1, 4, 7, 10 …
Monopicolinate cross-bridged cyclam combining very fast complexation with very high stability and inertness of its copper (II) complex
LMP Lima, Z Halime, R Marion, N Camus… - Inorganic …, 2014 - ACS Publications
The synthesis of a new cross-bridged 1, 4, 8, 11-tetraazacyclotetradecane (cb-cyclam)
derivative bearing a picolinate arm (H cb-te1pa) was achieved by taking advantage of the …
derivative bearing a picolinate arm (H cb-te1pa) was achieved by taking advantage of the …
Multisite thrombus imaging and fibrin content estimation with a single whole-body PET scan in rats
Objective—Thrombosis is a leading cause of morbidity and mortality worldwide. Current
diagnostic strategies rely on imaging modalities that are specific for distinct vascular …
diagnostic strategies rely on imaging modalities that are specific for distinct vascular …