Neglected tropical diseases (NTDs) encompass a group of infectious diseases with a
protozoan etiology, high incidence, and prevalence in developing countries. As a result …

ABSTRACT Introduction: Chagas disease affects 8–10 million people worldwide, mainly in
Latin America. The current therapy for Chagas disease is limited to nifurtimox and …

Sialidases (SAs) and sialyltransferases (STs), the enzymes responsible for removing and
adding sialic acid to other glycans, play essential roles in viruses, bacteria, parasites, and …

Background: Parasitic diseases caused by protozoa, such as Chagas disease,
leishmaniasis, malaria, African trypanosomiasis, amoebiasis, trichomoniasis, and giardiasis …

Chagas disease (CD) is a neglected disease caused by the parasite Trypanosoma cruzi,
which affects underdeveloped countries. The current drugs of choice are nifurtimox and …

The last decades have produced a plethora of evidence on the role of glycans, from cell
adhesion to signaling pathways. Much of that information pertains to their role on the …

In the current research, the main attention was to overcome solubility related issues of
atorvastatin (AC), and curcumin (CUR) through atorvastatin-curcumin conjugate (AC-CUR) …

Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per
year in the Americas. Current medical therapy for CD has low efficacy in the chronic phase …

Chagas´ disease continues to be a challenging and neglected public health problem in
many American countries. The etiologic agent, Trypanosoma cruzi, develops intracellularly …

Chagas disease is an infectious tropical disease included within the group of neglected
tropical diseases. Though historically endemic to Latin America, it has lately spread to high …