Synthesis of heterocycles via electrophilic cyclization of alkynes containing heteroatom
The interest in synthesizing heterocycles has always been enormous. The literature contains
a variety of synthetic approaches to the heterocycle ring structures, much of which has been …
a variety of synthetic approaches to the heterocycle ring structures, much of which has been …
Arylglyoxals in synthesis of heterocyclic compounds
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …
Cyclizations of alkynes: revisiting Baldwin's rules for ring closure
K Gilmore, IV Alabugin - Chemical Reviews, 2011 - ACS Publications
According to the CRC dictionary of natural products, 1 90% of chemically individual
molecules discovered in nature contain either a carbocyclic or a heterocyclic subunit. 2 Not …
molecules discovered in nature contain either a carbocyclic or a heterocyclic subunit. 2 Not …
Recent developments in the synthesis of five‐and six‐membered heterocycles using molecular iodine
PT Parvatkar, PS Parameswaran… - Chemistry–A European …, 2012 - Wiley Online Library
Heterocyclic scaffolds represent the key structural subunits of many biologically active
compounds. Over the last few years iodine‐mediated reactions have been extensively …
compounds. Over the last few years iodine‐mediated reactions have been extensively …
Comprehensive strategies for the synthesis of isoquinolines: Progress Since 2008
R Gujjarappa, N Vodnala… - Advanced Synthesis & …, 2020 - Wiley Online Library
In the past decades, an enormous number of reports have been dedicated towards the
synthesis of nitrogen containing heterocycles. This immense interest have emerged owing to …
synthesis of nitrogen containing heterocycles. This immense interest have emerged owing to …
Concerted reactions that produce diradicals and zwitterions: electronic, steric, conformational, and kinetic control of cycloaromatization processes
RK Mohamed, PW Peterson, IV Alabugin - Chemical Reviews, 2013 - ACS Publications
The broad utility of cyclic structures accounts for the key roles that cycle-forming reactions
play in synthetic designs. Most of these reactions can be classified as either a cyclization of …
play in synthetic designs. Most of these reactions can be classified as either a cyclization of …
Rh (III)-catalyzed C–H functionalization/aromatization cascade with 1, 3-dienes: a redox-neutral and regioselective access to isoquinolines
An efficient rhodium (III)-catalyzed redox-neutral C–H activation/cyclization/isomerization
strategy to prepare isoquinolines with complete regioselectivity from aromatic oxime esters …
strategy to prepare isoquinolines with complete regioselectivity from aromatic oxime esters …
Iodine-mediated synthesis of heterocycles via electrophilic cyclization of alkynes
T Aggarwal, S Kumar, AK Verma - Organic & biomolecular chemistry, 2016 - pubs.rsc.org
Iodine has been recognized as an efficient, non-toxic, readily available and easy-to-handle
electrophilic reagent to favour halocyclization reactions for the synthesis of novel …
electrophilic reagent to favour halocyclization reactions for the synthesis of novel …
[HTML][HTML] Metal-free intermolecular formal cycloadditions enable an orthogonal access to nitrogen heterocycles
Nitrogen-containing heteroaromatic cores are ubiquitous building blocks in organic
chemistry. Herein, we present a family of metal-free intermolecular formal cycloaddition …
chemistry. Herein, we present a family of metal-free intermolecular formal cycloaddition …
Metal Free Sulfonylative Spirocyclization of Alkenyl and Alkynyl Amides via Insertion of Sulfur Dioxide
Herein, we report an efficient synthesis of azaspiro [4, 5]‐decanes and azaspiro [4, 5]‐
trienones by the radical cascade spirocyclization of N‐benzylacrylamides or N …
trienones by the radical cascade spirocyclization of N‐benzylacrylamides or N …