Peptides and proteins have been found to possess an inherent tendency to convert from
their native functional states into intractable amyloid aggregates. This phenomenon is …

Protein aggregation is common to dozens of diseases including prionoses, diabetes,
Parkinson's and Alzheimer's. Over the past 15 years, there has been a paradigm shift in …

INTRODUCTION In Alzheimer's disease (AD), the production of amyloid β (Aβ) oligomers
and downstream tau dysfunction are thought to cause neuronal damage, in particular a loss …

This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

Alzheimer's disease (AD) is the most common form of dementia in the elderly, and affects
millions of people worldwide. As the number of AD cases continues to increase in both …

Localized surface plasmon resonance (LSPR) spectroscopy of metallic nanoparticles is a
powerful technique for chemical and biological sensing experiments. Moreover, the LSPR is …

The'toxic Aβ oligomer'hypothesis has attracted considerable attention among Alzheimer's
disease researchers as a way of resolving the lack of correlation between deposited amyloid …

Increasing evidence has shown the aberrant expression of inflammasome-related proteins
in Alzheimer's disease (AD) brain; these proteins, including NLRP1 inflammasome, are …

Converging lines of evidence suggest that progressive accumulation of the amyloid β‐
protein (Aβ) plays a central role in the genesis of Alzheimer's disease, but it was long …

Alzheimer's disease (AD) is an age‐related, progressive degenerative disorder that is
characterized by synapse and neuron loss in the brain and the accumulation of protein …