Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …

This article discusses the potential of Zebrafish (ZF)(Danio Rerio), as a model for epilepsy
research. Epilepsy is a neurological disorder affecting both children and adults, and many …

A neural stimulation technique that can inhibit neural activity reversibly and directly without
genetic modification is valuable for understating complex brain functions and treating brain …

System xc− exchanges intracellular glutamate for extracellular cystine, giving it a potential
role in intracellular glutathione synthesis and nonvesicular glutamate release. We report that …

A subset of central glutamatergic synapses are coordinately pruned and matured by
unresolved mechanisms during postnatal development. We report that the human epilepsy …

The Kv2. 1 delayed rectifier potassium channel exhibits high‐level expression in both
principal and inhibitory neurons throughout the central nervous system, including prominent …

Evidence from both preclinical and clinical studies suggest the importance of zinc
homeostasis in seizures/epilepsy. Undoubtedly, zinc, via modulation of a variety of targets, is …

The need to use animal models to develop imaging markers that could be linked to
electrophysiological abnormalities in epilepsy and able to predict epileptogenicity in human …

Epilepsy is a chronic brain disease and, considering the amount of people affected of all
ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure …

Idiopathic generalized epilepsy (IGE) syndromes represent about 30% of all epilepsies.
They have strong, but elusive, genetic components and sex-specific seizure expression …