Gold nanoparticles as a biosensor for cancer biomarker determination

CH Li, MH Chan, YC Chang, M Hsiao - Molecules, 2023 - mdpi.com
Molecular biology applications based on gold nanotechnology have revolutionary impacts,
especially in diagnosing and treating molecular and cellular levels. The combination of …

Current advances in detecting genetic and epigenetic biomarkers of colorectal cancer

MS Islam, V Gopalan, AKY Lam… - Biosensors and …, 2023 - Elsevier
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, such as …

Convergence of surface-enhanced Raman scattering with molecular diagnostics: a perspective on future directions

N Choi, S Schlücker - ACS nano, 2024 - ACS Publications
Molecular diagnostics (MD) is widely employed in multiple scientific disciplines, such as
oncology, pathogen detection, forensic investigations, and the pharmaceutical industry …

[HTML][HTML] SERS-based methods for the detection of genomic biomarkers of cancer

A Issatayeva, E Farnesi, D Cialla-May, M Schmitt… - Talanta, 2023 - Elsevier
Genomic biomarkers of cancer are based on changes in nucleic acids, which include
abnormal expression levels of some miRNAs, point mutations in DNA sequences, and …

Real-time investigation of intracellular polynucleotide kinase using a cascaded amplification circuit

J Shang, S Yu, Y Chen, Y Gao, C Hong, F Li… - Analytical …, 2021 - ACS Publications
Polynucleotide kinase (PNK) shows an in-depth correlationship with DNA repair and
metabolism processes. The in situ visualization of intracellular PNK revealed an extremely …

Invader assay-induced catalytic assembly of multi-DNAzyme junctions for sensitive detection of single nucleotide polymorphisms

X Li, L Liao, B Jiang, R Yuan, Y Xiang - Analytica Chimica Acta, 2022 - Elsevier
Single nucleotide polymorphisms (SNPs) are main causes of differences in human
phenotypes and drug resistance, especially the development of genetic diseases …

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

Y Chen, S Zheng, X Tang, F Wang… - Chemistry–An Asian …, 2023 - Wiley Online Library
Timely and powerful diagnostic means can achieve better therapeutic effects, reduce
disease torment, and improve survival rate. As a powerful non‐invasive spectroscopy …

An efficient extraction method for short single-stranded DNA from agarose gels in aptamer screening

C Pu, X Liao, X Shi, Y Cui, Y Bai, LL Chen - International Journal of …, 2023 - Elsevier
With the rapid advancements in aptamer screening, the efficient extraction of short single-
stranded DNA (ssDNA) from agarose gel has become a new requirement. However, the …

Recent Progress in Single-Nucleotide Polymorphism Biosensors

K Wu, F Kong, J Zhang, Y Tang, Y Chen, L Chao, L Nie… - Biosensors, 2023 - mdpi.com
Single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in the
human genome, are the main cause of individual differences. Furthermore, such attractive …

SERS biosensors for liquid biopsy towards cancer diagnosis by detection of various circulating biomarkers: current progress and perspectives

N Lyu, A Hassanzadeh-Barforoushi, LM Rey Gomez… - Nano …, 2024 - Springer
Liquid biopsy has emerged as a promising non-invasive strategy for cancer diagnosis,
enabling the detection of various circulating biomarkers, including circulating tumor cells …