Transposable elements in Drosophila

V Mérel, M Boulesteix, M Fablet, C Vieira - Mobile DNA, 2020 - Springer
Drosophila has been studied as a biological model for many years and many discoveries in
biology rely on this species. Research on transposable elements (TEs) is not an exception …

The diversity of LTR retrotransposons

ER Havecker, X Gao, DF Voytas - Genome biology, 2004 - Springer
Eukaryotic genomes are full of long terminal repeat (LTR) retrotransposons. Although most
LTR retrotransposons have common structural features and encode similar genes, there is …

Transposable elements: powerful facilitators of evolution

KR Oliver, WK Greene - Bioessays, 2009 - Wiley Online Library
Transposable elements (TEs) are powerful facilitators of genome evolution, and hence of
phenotypic diversity as they can cause genetic changes of great magnitude and variety. TEs …

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

D Olivieri, MM Sykora, R Sachidanandam… - The EMBO …, 2010 - embopress.org
In Drosophila, PIWI proteins and bound PIWI‐interacting RNAs (piRNAs) form the core of a
small RNA‐mediated defense system against selfish genetic elements. Within germline …

The piRNA pathway: a fly's perspective on the guardian of the genome

KA Senti, J Brennecke - Trends in Genetics, 2010 - cell.com
Throughout the eukaryotic lineage, small RNA silencing pathways protect the genome
against the deleterious influence of selfish genetic elements such as transposons. In …

Transovarial transmission of a plant virus is mediated by vitellogenin of its insect vector

Y Huo, W Liu, F Zhang, X Chen, L Li, Q Liu… - PLoS …, 2014 - journals.plos.org
Most plant viruses are transmitted by hemipteroid insects. Some viruses can be transmitted
from female parent to offspring usually through eggs, but the mechanism of this transovarial …

Rapid evolution and conserved function of the piRNA pathway

SS Parhad, WE Theurkauf - Royal Society Open Biology, 2019 - royalsocietypublishing.org
Transposons are major genome constituents that can mobilize and trigger mutations, DNA
breaks and chromosome rearrangements. Transposon silencing is particularly important in …

Viral reverse transcriptases

L Menéndez-Arias, A Sebastián-Martín, M Álvarez - Virus research, 2017 - Elsevier
Reverse transcriptases (RTs) play a major role in the replication of Retroviridae,
Metaviridae, Pseudoviridae, Hepadnaviridae and Caulimoviridae. RTs are enzymes that are …

Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line

NC Lau, N Robine, R Martin, WJ Chung, Y Niki… - Genome …, 2009 - genome.cshlp.org
Piwi proteins, a subclass of Argonaute-family proteins, carry∼ 24–30-nt Piwi-interacting
RNAs (piRNAs) that mediate gonadal defense against transposable elements (TEs). We …

Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

MH Fabry, FA Falconio, F Joud, EK Lythgoe, B Czech… - Elife, 2021 - elifesciences.org
Abstract The PIWI-interacting RNA (piRNA) pathway controls transposon expression in
animal germ cells, thereby ensuring genome stability over generations. In Drosophila …