Harnessing genomic information for livestock improvement
M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …
2050. Meeting this demand in a way that has a minimal impact on the environment will …
Genomics and the future of conservation genetics
We will soon have complete genome sequences from thousands of species, as well as from
many individuals within species. This coming explosion of information will transform our …
many individuals within species. This coming explosion of information will transform our …
Mapping genes for complex traits in domestic animals and their use in breeding programmes
ME Goddard, BJ Hayes - Nature Reviews Genetics, 2009 - nature.com
Genome-wide panels of SNPs have recently been used in domestic animal species to map
and identify genes for many traits and to select genetically desirable livestock. This has led …
and identify genes for many traits and to select genetically desirable livestock. This has led …
Genomics advances the study of inbreeding depression in the wild
Inbreeding depression (reduced fitness of individuals with related parents) has long been a
major focus of ecology, evolution, and conservation biology. Despite decades of research …
major focus of ecology, evolution, and conservation biology. Despite decades of research …
The future of livestock breeding: genomic selection for efficiency, reduced emissions intensity, and adaptation
As the global population and global wealth both continue to increase, so will the demand for
livestock products, especially those that are highly nutritious. However, competition with …
livestock products, especially those that are highly nutritious. However, competition with …
Endoplasmic-reticulum calcium depletion and disease
D Mekahli, G Bultynck, JB Parys… - Cold Spring …, 2011 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) as an intracellular Ca2+ store not only sets up cytosolic
Ca2+ signals, but, among other functions, also assembles and folds newly synthesized …
Ca2+ signals, but, among other functions, also assembles and folds newly synthesized …
Calcium pumps in health and disease
M Brini, E Carafoli - Physiological reviews, 2009 - journals.physiology.org
Ca2+-ATPases (pumps) are key actors in the regulation of Ca2+ in eukaryotic cells and are
thus essential to the correct functioning of the cell machinery. They have high affinity for …
thus essential to the correct functioning of the cell machinery. They have high affinity for …
The future of ancient DNA: technical advances and conceptual shifts
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
[HTML][HTML] Harmful recessive effects on fertility detected by absence of homozygous haplotypes
PM VanRaden, KM Olson, DJ Null, JL Hutchison - Journal of dairy science, 2011 - Elsevier
Five new recessive defects were discovered in Holsteins, Jerseys, and Brown Swiss by
examining haplotypes that had a high population frequency but were never homozygous …
examining haplotypes that had a high population frequency but were never homozygous …
Inbreeding depression in livestock species: review and meta‐analysis
G Leroy - Animal genetics, 2014 - Wiley Online Library
Inbreeding, by virtue of its consequence on traits of interest, is a topic of major interest for
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …