Historically, the field of regenerative medicine has aimed to heal damaged tissue through
the use of biomaterials scaffolds or delivery of foreign progenitor cells. Despite 30 years of …

Human stem cell derived brain organoids are increasingly gaining attention as an ideal
model system for investigating neurological diseases, particularly those that involve …

The central nervous system (CNS), consisting of the brain and spinal cord, regulates the
mind and functions of the organs. CNS diseases, leading to changes in neurological …

Liver extracellular matrix (ECM)-based hydrogels have gained considerable interest as
biomimetic 3D cell culture environments to investigate the mechanisms of liver pathology …

Hydrogel based matrices and titanium dioxide (TiO 2) nanoparticles (NPs) are well
established materials in bone tissue engineering. Nevertheless, there is still a challenge to …

Aging is a major risk factor for many neurodegenerative diseases. Klotho (KL) is a
glycosylated transmembrane protein that is expressed in the choroid plexus and neurons of …

Decellularization to produce bioscaffolds composed of the extracellular matrix (ECM) uses
enzymatic, chemical and physical methods to remove antigens and cellular components …

Herein, a PVA (polyvinyl alcohol)-based multi-responsive hydrogel was prepared by
introducing the dynamic and reversible supramolecular complexation between polyvinyl …

Although small cell lung cancer (SCLC) is characterized by early metastasis and high
resistance to most anti-cancer therapeutics, resulting in poor prognosis, surgical treatment is …

Neural epidermal growth factor-like like 2 (NELL2) is a cytoplasmic and secreted
glycosylated protein with six epidermal growth factor-like domains. In animal models, NELL2 …