Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates
multiple biological processes, including cell division, DNA replication/repair, signal …

Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now
established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds …

The regulation of protein fate by modification with the small ubiquitin-related modifier
(SUMO) plays an essential and crucial role in most cellular pathways. Sumoylation is highly …

A decade has passed since SUMO (small ubiquitin-related modifier) was discovered to be a
reversible post-translational protein modifier. During this time many enzymes that participate …

Structural maintenance of chromosomes (SMC) complexes are ubiquitous genome
regulators with a wide range of functions. Among the three types of SMC complexes in …

The repair of DNA lesions that occur endogenously or in response to diverse genotoxic
stresses is indispensable for genome integrity. DNA lesions activate checkpoint pathways …

The post-translational modification SUMOylation is a major regulator of protein function that
plays an important role in a wide range of cellular processes. SUMOylation involves the …

The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are
cancer-testis antigens that are highly expressed in cancer and play a critical role in …

Heterochromatin mostly comprises repeated sequences prone to harmful ectopic
recombination during double-strand break (DSB) repair. In Drosophila …

Alternative lengthening of telomeres (ALT) is a telomerase-independent telomere
maintenance mechanism that occurs in a subset of cancers. By analyzing telomerase …